Perampanel Impurity 59 CAS CATO-C4X-243059
| CAS No. | CATO-C4X-243059 |
| Molecular Formula | C16H10Br2N2O |
| Molecular Weight | 406.07 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Perampanel Impurity 59 (C16H10Br2N2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 406.07 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a process- or degradation-related impurity, Perampanel Impurity 59 (CAS CATO-C4X-243059, C16H10Br2N2O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H10Br2N2O |
| Molecular Weight | 406.07 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Perampanel Standards
- Perampanel Impurity 34 (CAS CATO-C4X-243034)
- Perampanel impurity 41 (CAS CATO-C4X-243041)
- Perampanel impurity 49 (CAS CATO-C4X-243049)
- Perampanel Impurity 52 (CAS CATO-C4X-243052)
- Perampanel Impurity 10 (CAS CATO-C4X-243010)
- Perampanel Impurity 24 (CAS CATO-C4X-243024)
- Perampanel Impurity 26 (CAS CATO-C4X-243026)
- Perampanel Impurity 11 (CAS CATO-C4X-243011)
Recommended Standards
- 4',7'-Dibromodispiro[1,3-dioxolane-2,3'-tricyclo[5.2.1.0,2,6]decane-10',2''-[1,3]dioxolane]-4',8'-diene (CAS 485318-53-4)
- (3Z)-N-(2,4-Dichlorophenyl)-3-{[(2,4-dichlorophenyl)methoxy]imino}propanamide (CAS 477851-45-9)
- 4,6-Bis(4-bromophenyl)-1,3,5-triazin-2-amine (CAS 866018-86-2)
- (3Z)-N-(2,4-Dichlorophenyl)-3-{[(3,4-dichlorophenyl)methoxy]imino}propanamide (CAS 477851-46-0)
- Benproperine Impurity 3 (CAS 85909-36-0)
- Metformin Impurity 19 (CAS CATO-C4X-122019)
- Ibrutinib Impurity 25 (CAS CATO-C4X-106425)
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