Rimegepant Impurity 141 CAS CATO-C4X-2487141
| CAS No. | CATO-C4X-2487141 |
| Molecular Formula | C28H25F2N5O4 |
| Molecular Weight | 533.53 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Rimegepant Impurity 141 (CAS CATO-C4X-2487141), a pharmacopoeial impurity reference standard (molecular formula C28H25F2N5O4, MW 533.53 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Rimegepant Impurity 141 (C28H25F2N5O4) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), Rimegepant Impurity 141 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C28H25F2N5O4 |
| Molecular Weight | 533.53 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
Related Rimegepant Standards
- Rimegepant Impurity 144 (CAS CATO-C4X-2487144)
- Rimegepant Impurity 33 (CAS CATO-C4X-248733)
- Rimegepant (CAS 1289023-67-1)
- Rimegepant Impurity 127 (CAS CATO-C4X-2487127)
- Rimegepant Impurity 153 (CAS CATO-C4X-2487153)
- Rimegepant Impurity 39 (CAS CATO-C4X-248739)
- Rimegepant Impurity 40 (CAS CATO-C4X-248740)
- Rimegepant Impurity 41 (CAS CATO-C4X-248741)
Recommended Standards
- Methyltetrazine-PEG5-NHS ester (CAS 1802907-92-1)
- Sodium 2-(5-((6-(5-(tert-butyl)benzo[d]oxazol-2-yl)naphthalen-2-yl)oxy)pentyl)malonate (CAS 654080-03-2)
- Fulvestrant impurity 47 (CAS CATO-C4X-191747)
- 2-((3-Cyano-6-(4-methoxyphenyl)-4-(trifluoromethyl)pyridin-2-yl)thio)-N-(3,4,5-trimethoxyphenyl)acetamide (CAS 625377-98-2)
- Vilazodone impurity 02 (CAS 163521-11-7)
- Acesulfame impurity 4 (CAS 459454-05-8)
- Trilaciclib impurity 15 (CAS CATO-C4X-304415)
- Ethyl (1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)carbamate (CAS 10077-97-1)
- 2-[(thiophen-2-yl)methyl]-3h-imidazo[4,5-b]pyridin-5-amine (CAS 1519763-40-6)
- 6-Iodo-3-methylpyrimidine-2,4(1H,3H)-dione (CAS 21428-18-2)
- 2-({[2-({[2-Carboxycyclohexyl]carbonyl}anilino)ethyl]anilino}carbonyl)cyclohexanecarboxylic acid (CAS 1212289-11-6)
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- 2-(4-Chlorobenzenesulfonamido)benzoic acid (CAS 51012-31-8)
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Why CATO?
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