Rimegepant Impurity 149 CAS CATO-C4X-2487149

Purity ≥95%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-2487149
Molecular FormulaC18H18F2N2O2
Molecular Weight332.34 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Rimegepant Impurity 149 CAS CATO-C4X-2487149 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 332.34 g/mol gives Rimegepant Impurity 149 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Rimegepant Impurity 149 (CAS CATO-C4X-2487149), a pharmacopoeial impurity reference standard (molecular formula C18H18F2N2O2, MW 332.34 g/mol) used for the identification and quantification of trace impurities in APIs.

Based on its molecular formula C18H18F2N2O2, Rimegepant Impurity 149 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 332.34 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

As a certified reference material (CRM), Rimegepant Impurity 149 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC18H18F2N2O2
Molecular Weight332.34 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity≥95%
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Halogen ContentF-containing
Nitrogen Atoms2

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