Rimegepant Impurity 154 CAS CATO-C4X-2487154
| CAS No. | CATO-C4X-2487154 |
| Molecular Formula | C45H42F4N8O5 |
| Molecular Weight | 850.86 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Rimegepant Impurity 154 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Rimegepant Impurity 154 (CAS CATO-C4X-2487154, C45H42F4N8O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Rimegepant Impurity 154 (C45H42F4N8O5) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C45H42F4N8O5 |
| Molecular Weight | 850.86 g/mol |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 27.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 8 |
Related Rimegepant Standards
- Rimegepant Impurity 157 (CAS CATO-C4X-2487157)
- Rimegepant Impurity 155 (CAS CATO-C4X-2487155)
- Rimegepant Impurity 156 (CAS CATO-C4X-2487156)
- Rimegepant Impurity 37 (CAS CATO-C4X-248737)
- Rimegepant Impurity 158 (CAS CATO-C4X-2487158)
- Rimegepant Impurity 132 (CAS CATO-C4X-2487132)
- Rimegepant Impurity 8 (CAS CATO-C4X-24878)
- Rimegepant Impurity 106 (CAS CATO-C4X-2487106)
Recommended Standards
- IID610-2B (CAS 2227382-74-1)
- (6,8-dibromo-3,4-dihydro-2H-thieno[3,4-b][1,4]dioxepine-3,3-diyl)bis(methylene) bis(2-hexyldecanoate) (CAS 2882848-55-5)
- Mono-POC tenofovir dimer (CAS 1401420-56-1)
- Leucokinin II H-Asp-Pro-Gly-Phe-Ser-Ser-Trp-Gly-NH2 (CAS 104821-31-0)
- Diosmin EP Impurity D (CAS 1431536-92-3)
- Afatinib Impurity 65 (CAS CATO-C4X-100665)
- Clindamycin Phosphas Impurity 40 (CAS CATO-C4X-134140)
- H-Phe-Gly-Phe-Gly-OH (CAS 59005-83-3)
- 2-Propenoic acid, 2-methyl-, methyl ester, polymer with ethenylbenzene and 2-propenenitrile (CAS 25213-88-1)
- Diazoxide Impurity 16 (CAS 576997)
- trans-3-fluoro-tetrahydro-2H-pyran-4-yl methanesulfonate racemate (CAS 1864003-09-7)
- Flunarizine Impurity 17 (CAS 17730-78-8)
- 3-(3,3-Difluoroazetidin-1-yl)piperidine (CAS 2366179-60-2)
- Semaglutide impurity 63 (CAS CATO-C4X-222663)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com