Venetoclax Impurity 40 CAS CATO-C4X-249540
| CAS No. | CATO-C4X-249540 |
| Molecular Formula | C32H35ClN4O |
| Molecular Weight | 527.10 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Venetoclax Impurity 40 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 527.10 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Venetoclax Impurity 40 (CAS CATO-C4X-249540), a pharmacopoeial impurity reference standard (molecular formula C32H35ClN4O, MW 527.10 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C32H35ClN4O |
| Molecular Weight | 527.10 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Venetoclax Standards
- Venetoclax Impurity 89 (CAS CATO-C4X-249589)
- Venetoclax Impurity 11 (CAS CATO-C4X-249511)
- Venetoclax Impurity 39 (CAS CATO-C4X-249539)
- Venetoclax Impurity 10 (CAS CATO-C4X-249510)
- Venetoclax Impurity 37 (CAS CATO-C4X-249537)
- Venetoclax Impurity 113 (CAS CATO-C4X-2495113)
- Venetoclax Impurity 135 (CAS CATO-C4X-2495135)
- Venetoclax Impurity 147 (CAS CATO-C4X-2495147)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com