Malic Acid Impurity 12 CAS CATO-C4X-250912
| CAS No. | CATO-C4X-250912 |
| Molecular Formula | C6H8O6 |
| Molecular Weight | 176.12 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Malic Acid Impurity 12.
Malic Acid Impurity 12 (CAS CATO-C4X-250912) is a certified pharmaceutical impurity reference standard with the molecular formula C6H8O6 and a molecular weight of 176.12 g/mol.
Malic Acid Impurity 12 (C6H8O6) contains a carbohydrate-derived structure. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Malic Acid Impurity 12 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H8O6 |
| Molecular Weight | 176.12 g/mol |
| Purity | ＞95% |
| Storage | Store at 2-8°C, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
Related Malic Standards
- Malic acid (disodium salt) (CAS 676-46-0)
- Malic Acid Impurity 13 (CAS CATO-C4X-250913)
- Malic Acid Impurity 14 (CAS CATO-C4X-250914)
- Malic Acid Impurity 15 (CAS 71901-42-3)
- Malic Acid Impurity 15 (CAS 4198-33-8)
- Malic Acid Impurity 2 (CAS 140235-34-3)
- Malic Acid Impurity 3 (CAS 66178-02-7)
- Malic Acid Impurity 6 (CAS 63640-09-5)
Recommended Standards
- L-(+)-Ascorbic Acid (CAS 50-81-7)
- D-Glucuronic Acid Lactone (CAS 32449-92-6)
- Ascorbic Acid EP Impurity F (CAS 89-65-6)
- 1,2,3-Propanetricarboxylic Acid (CAS 99-14-9)
- Posaconazole Impurity 46 (CAS CATO-C4X-120846)
- Nebivolol Impurity 97 (CAS CATO-C4X-196897)
- Carbazochrome Impurity 9 Sodium Salt (CAS CATO-C4X-22919)
- 1-(2,4,6-Trifluorophenyl)ethanol (CAS 1250113-83-7)
- Dioctyl (2-(dimethylamino)-2-oxoethyl)phosphonate (CAS 83631-23-6)
- 4-Cyanothiazole (CAS 1452-15-9)
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- 4-Hydroxy Ethynyl Estradiol (CAS 50394-90-6)
- 3-(2-Aminoethyl)-4-methoxy-indole Hydrochloride (CAS 26579-75-9)
- Sperm Activating Peptide, Sea Urchin (CAS 140653-27-6)
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