Pitolisant impurity 12 CAS CATO-C4X-252012
| CAS No. | CATO-C4X-252012 |
| Molecular Formula | C17H26ClNO |
| Molecular Weight | 295.85 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Pitolisant impurity 12 is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Pitolisant impurity 12 (CAS CATO-C4X-252012) is a certified pharmaceutical impurity reference standard with the molecular formula C17H26ClNO and a molecular weight of 295.85 g/mol.
Pitolisant impurity 12 (C17H26ClNO) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H26ClNO |
| Molecular Weight | 295.85 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Pitolisant Standards
- Pitolisant (CAS 362665-56-3)
- Pitolisant impurity 6 (CAS CATO-C4X-25206)
- Pitolisant impurity 9 (CAS CATO-C4X-25209)
- Pitolisant impurity 35 (CAS CATO-C4X-252035)
- Pitolisant impurity 19 (CAS CATO-C4X-252019)
- Pitolisant Impurity 51 (CAS CATO-C4X-252051)
- Pitolisant Impurity 54 (CAS CATO-C4X-252054)
- Pitolisant impurity 33 (CAS CATO-C4X-252033)
Recommended Standards
- Venlafaxine Impurity 42 (CAS CATO-C4X-143442)
- 1-(2-Chloropyridin-4-yl)dodecan-1-one (CAS 898784-80-0)
- 4'-Methyl-α-pyrrolidinohexanophenone Hydrochloride (CAS 1391052-36-0)
- (3-Fluoro-2-iodo-5-methoxyphenyl)boronic acid (CAS 1227633-12-6)
- Imrecoxib Impurity 11 (CAS 896729-07-0)
- Posaconazole Impurity 63 (CAS CATO-C4X-120863)
- Ceritinib Impurity 61 (CAS CATO-C4X-104861)
- Ethyl 2-(4-aminopiperidin-1-yl)acetate (CAS 172967-30-5)
- 2-(2-Hydroxyethyl)-1H-benz[f]isoindole-1,3(2H)-dione (CAS 6345-88-6)
- N-(3-Ethynylphenyl)acetamide (CAS 70933-58-3)
- N-(1-Cyanocyclohexyl)-2-((5,7-dichloro-2-methylquinolin-8-yl)oxy)acetamide (CAS 732996-55-3)
- (4-(6-Methyl-1H-benzo[d]imidazol-2-yl)cyclohexyl)methanamine (CAS 933682-43-0)
- N'-(3,5-Dibromopyrazin-2-yl)-N-hydroxyformimidamide (CAS 60420-05-5)
- Semaglutide impurity 211 (CAS CATO-C4X-2226211)
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