Pitolisant impurity 18 CAS CATO-C4X-252018
| CAS No. | CATO-C4X-252018 |
| Molecular Formula | C15H22ClNO |
| Molecular Weight | 267.79 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Pitolisant impurity 18 (C15H22ClNO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 267.79 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Pitolisant impurity 18 (CAS CATO-C4X-252018), a pharmacopoeial impurity reference standard (molecular formula C15H22ClNO, MW 267.79 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H22ClNO |
| Molecular Weight | 267.79 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Pitolisant Standards
- Pitolisant impurity 22 (CAS 110129-10-7)
- Pitolisant impurity 7 (CAS 362665-54-1)
- Pitolisant Impurity 50 (CAS 90562-26-8)
- Pitolisant impurity 15 (CAS CATO-C4X-252015)
- Pitolisant impurity 20 (CAS CATO-C4X-252020)
- Pitolisant impurity 31 (CAS CATO-C4X-252031)
- Pitolisant impurity 14 (CAS CATO-C4X-252014)
- Pitolisant Impurity 51 (CAS CATO-C4X-252051)
Recommended Standards
- n-[2,6-bis(propan-2-yl)phenyl]-3-chloropropanamide (CAS 930395-70-3)
- 4-[4-(3-Chlorophenyl)piperazino]butylamine (CAS 116331-14-7)
- 4-Chloro-N,N-diisobutylbenzamide (CAS 7461-44-1)
- (R)-3-Chloro-1-phenyl-1-(2-methylphenoxy-d7)propane (CAS 1217765-70-2)
- Teneligliptin (2R,4R)-Isomer Impurity HBr (CAS 1404559-17-6(free base))
- Hydrocortisone Impurity 74 (CAS CATO-C4X-140174)
- Iohexol Impurity 16 (CAS 76820-34-3)
- Lansoprazole-d4 (CAS 934294-22-1)
- 2-Ethynylnicotinonitrile (CAS 132898-81-8)
- 2-(Pyrrolidin-1-yl)pyrimidine-5-carboxylic acid (CAS 253315-06-9)
- 2-Methyl-5-[4-(tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-1,3,4-oxadiazole (CAS 1056456-24-6)
- 1-tert-Butyl 5-methyl 3-bromo-1H-indazole-1,5-dicarboxylate (CAS 473416-13-6)
- 4-(Cyanomethyl)benzoic Acid (CAS 50685-26-2)
- Semaglutide Impurity 2 (CAS CATO-C4X-22262)
Why CATO?
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