Amoxapine Impurity 2 CAS CATO-C4X-25822
| CAS No. | CATO-C4X-25822 |
| Molecular Formula | C17H15ClN4O2 |
| Molecular Weight | 342.78 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Amoxapine Impurity 2.
CATO supplies Amoxapine Impurity 2 (CAS CATO-C4X-25822), a pharmacopoeial impurity reference standard (molecular formula C17H15ClN4O2, MW 342.78 g/mol) used for the identification and quantification of trace impurities in APIs.
Amoxapine Impurity 2 (C17H15ClN4O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H15ClN4O2 |
| Molecular Weight | 342.78 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Amoxapine Standards
- Amoxapine RC 9 (CAS 47439-36-1)
- Amoxapine Impurity 10 (8-Hydroxyamoxapine) (CAS 61443-78-5)
- Amoxapine-D8 (CAS 1189671-27-9)
- Amoxapine (CAS 14028-44-5)
- Amoxapine Chlorophenoxyaniline Carbamate (CAS 31879-60-4)
- Amoxapine Impurity 3 (CAS 21636-40-8)
- Amoxapine N-t-Butoxycarbonyl Impurity (CAS 1246816-84-1)
- Amoxapine Impurity 5 (CAS 5606-39-3)
Recommended Standards
- Tolvaptan impurity 113 (CAS CATO-C4X-1955113)
- [4-(6-Chloro-4-trifluoromethyl-pyridin-2-yl)-benzyl]-diethyl-amine (CAS 1311278-43-9)
- N-desmethyl N-Nitroso 4-Chloro phenyl Zolpidem (CAS CATO-C4X-148617)
- N1-(3-Chloro-4-fluorophenyl)-N2-(2-cyclohexyl-2-hydroxyethyl)oxalamide (CAS 1351584-96-7)
- Doxazosin impurity 21 (CAS CATO-C4X-162321)
- Istradefylline impurity 33 (CAS CATO-C4X-106133)
- Budesonide Impurity 19 (Mixture of Epimer) (CAS 192057-49-1)
- 5-(4-(Tert-butyl)phenyl)isoxazole-3-carboxylic acid (CAS 1017459-78-7)
- 1,1,1-Trimethyl-n-(triphenylphosphoranylidenE)silanamine (CAS 13892-06-3)
- 4-(Trimethylsilyl)aniline (CAS 17889-23-5)
- 2-Bromo-5-(cyclobutanoylamino)-pyridine (CAS 885267-03-8)
- 6-Cyclopropyl-2-oxo-4-(trifluoromethyl)-1,2-dihydropyridine-3-carbonitrile (CAS 861212-38-6)
- Tert-butyl (4-oxo-4-(piperazin-1-yl)butyl)carbamate (CAS 1308650-47-6)
- Peptide 442 (CAS CATO-CPTD788442)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com