Tucatinib Impurity 56（E-Isomer） CAS CATO-C4X-260556
| CAS No. | CATO-C4X-260556 |
| Molecular Formula | C15H19N5O3S |
| Molecular Weight | 349.41 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Tucatinib Impurity 56（E-Isomer） (CAS CATO-C4X-260556), a pharmacopoeial impurity reference standard (molecular formula C15H19N5O3S, MW 349.41 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Tucatinib Impurity 56（E-Isomer） (C15H19N5O3S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 349.41 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H19N5O3S |
| Molecular Weight | 349.41 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Tucatinib Standards
- Tucatinib Impurity 17 (CAS CATO-C4X-260517)
- Tucatinib Impurity 59 (CAS CATO-C4X-260559)
- Tucatinib Impurity 65 (CAS CATO-C4X-260565)
- Tucatinib Impurity 30 (CAS CATO-C4X-260530)
- Tucatinib Impurity 8 (CAS CATO-C4X-26058)
- Tucatinib Impurity 31 (CAS CATO-C4X-260531)
- Tucatinib Impurity 36 (CAS CATO-C4X-260536)
- Tucatinib Impurity 68 (CAS CATO-C4X-260568)
Recommended Standards
- N'-benzoyl-8-methyl-8H-thieno[2,3-b]indole-2-carbohydrazide (CAS 477855-73-5)
- Ac-Met-Ala-Ser-OH (CAS 149151-19-9)
- N7-(4-Methoxyphenyl)-N2-phenylthiazolo[5,4-d]pyrimidine-2,7-diamine (CAS 871266-93-2)
- Glutathione-monoisopropyl ester (reduced) (CAS 97451-46-2)
- Podophyllotoxin Impurity 1 (CAS 1173-42-8)
- Argatroban Impurity 54 (CAS CATO-C4X-100754)
- Nicardipine Impurity 63 (CAS CATO-C4X-171063)
- 3-(tert-Butyl)benzoic Acid (CAS 7498-54-6)
- 5-Methoxyfuran-2-carbaldehyde (CAS 21300-07-2)
- Vildagliptin Impurity 3 (CAS 565453-40-9)
- 1-[3-(cyclopentyloxy)phenyl]propan-2-amine hydrochloride (CAS 1311316-27-4)
- 2-Homomorpholinecarboxylic Acid Hydrochloride (CAS 1186663-62-6)
- N,N-Dimethyl-2-(1-pyrazolyl)ethanamine (CAS 1071658-18-8)
- Semaglutide impurity 73 (CAS CATO-C4X-222673)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com