Biphenyl Impurity 1 CAS CATO-C4X-26291
| CAS No. | CATO-C4X-26291 |
| Molecular Formula | C18H20N2O2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Biphenyl Impurity 1 (C18H20N2O2HCl) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Biphenyl Impurity 1 (CAS CATO-C4X-26291) is a certified pharmaceutical impurity reference standard with the molecular formula C18H20N2O2HCl and a molecular weight of 332.83 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Biphenyl Impurity 1 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H20N2O2 HCl |
| Molecular Weight | 332.83 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Biphenyl Standards
- 5-([1,1'-Biphenyl]-4-yl)-2-(2,4,6-trichlorophenyl)-1H-1,2,4-triazol-3(2H)-one (CAS 1000571-92-5)
- Ethyl 1-([1,1'-biphenyl]-4-yl)-5-oxo-2,5-dihydro-1H-1,2,4-triazole-3-carboxylate (CAS 1000572-17-7)
- 2-([1,1'-Biphenyl]-4-yl)-5-benzoyl-1H-1,2,4-triazol-3(2H)-one (CAS 1000575-27-8)
- N-([1,1'-biphenyl]-4-yl)-9-phenyl-9H-carbazol-3-amine (CAS 1002762-60-8)
- (2E)-1-{[1,1'-Biphenyl]-4-yl}-3-(2,3-dimethoxyphenyl)prop-2-en-1-one (CAS 1002798-81-3)
- (2E)-1-{[1,1'-Biphenyl]-4-yl}-3-(5-methylthiophen-2-yl)prop-2-en-1-one (CAS 1003448-23-4)
- Methyl 1-(([1,1'-biphenyl]-4-yloxy)methyl)-1h-pyrazole-3-carboxylate (CAS 1003988-82-6)
- 1-(([1,1'-biphenyl]-2-yloxy)methyl)-3,5-dimethyl-1h-pyrazol-4-amine (CAS 1004451-73-3)
Recommended Standards
- Glycerol Impurity 40 (CAS 64528-53-6)
- Landiolol Impurity 86 (CAS CATO-C4X-262186)
- Cholecalciferol Impurity 19 (CAS CATO-C4X-158619)
- Bis(2-methoxyethyl) sulfate (CAS 221655-54-5)
- 4-(1H-Imidazol-1-yl)-2-methyl-6-(piperazin-1-yl)pyrimidine (CAS 1706419-04-6)
- 6-(4-(Piperazin-1-yl)-3-(trifluoromethyl)phenyl)pyridazin-3(2H)-one (CAS 1187874-30-1)
- 4-Amino-n-(2-methylphenyl)benzene-1-sulfonamide (CAS 16803-96-6)
- [4-(ethylsulfamoyl)phenyl]boronic acid (CAS 871329-65-6)
- 4-Hydroxy phenyl acetic acid tert-butyl ester (CAS 16010-88-1)
- Semaglutide impurity 109 (CAS CATO-C4X-2226109)
Why CATO?
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