Tetrabenazine Impurity 12 CAS CATO-C4X-274812
| CAS No. | CATO-C4X-274812 |
| Molecular Formula | C18H27NO6 |
| Molecular Weight | 353.41 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Tetrabenazine Impurity 12 (CAS CATO-C4X-274812) is a certified pharmaceutical impurity reference standard with the molecular formula C18H27NO6 and a molecular weight of 353.41 g/mol.
The molecular framework of Tetrabenazine Impurity 12 (C18H27NO6) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), Tetrabenazine Impurity 12 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H27NO6 |
| Molecular Weight | 353.41 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | ＞95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Tetrabenazine Standards
- Tetrabenazine Impurity 13 (CAS CATO-C4X-274813)
- Tetrabenazine Impurity 15 (CAS 1256550-62-5)
- Tetrabenazine Impurity 45 (CAS CATO-C4X-274845)
- Tetrabenazine Impurity 46 (CAS CATO-C4X-274846)
- Tetrabenazine Impurity 28-D6 (CAS CATO-C4X-274828)
- Tetrabenazine Impurity 58 (CAS CATO-C4X-274858)
- Tetrabenazine Impurity 61 (CAS CATO-C4X-274861)
- Tetrabenazine metabolite (CAS 1688661-95-1)
Recommended Standards
- α-Hydroxy olopatadine (CAS 1628639-06-4)
- Olotadine lmpurity 54 (CAS CATO-C4X-171854)
- Olopatadine USP Related Compound B (CAS 173174-07-7)
- Finerenone Impurity 137 (CAS CATO-C4X-2880137)
- Ketoprofen EP Impurity J Sodium Salt (CAS CATO-C4X-147120)
- Econazole impurity 30 (CAS CATO-C4X-132730)
- Brivaracetam Impurity 87 (CAS CATO-C4X-200787)
- 7-Hydroxy-1H-indazole-3-carboxylic acid (CAS 1337882-49-1)
- 2-Hydrazinyl-5-methyl-4-(p-tolyl)thiazole (CAS 886494-57-1)
- 2,5-Dichlorophenylhydrazine Hydrochloride (CAS 50709-35-8)
- methyl({[trans-1-methyl-2-(1-methyl-1H-pyrazol-4-yl)piperidin-3-yl]methyl})amine (CAS 1808326-85-3)
- Cefamandole Impurity 12 (CAS CATO-C4X-122112)
- 3,4,5-Trichlorobenzoic acid (CAS 51-39-8)
- Semaglutide impurity 29 (CAS 110990-08-4)
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