Mebendazole impurity 3 CAS CATO-C4X-27683
| CAS No. | CATO-C4X-27683 |
| Molecular Formula | C16H12N4O4 |
| Molecular Weight | 324.29 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 324.29 g/mol gives Mebendazole impurity 3 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Mebendazole impurity 3 (CAS CATO-C4X-27683, C16H12N4O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Mebendazole impurity 3 (C16H12N4O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Mebendazole impurity 3 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H12N4O4 |
| Molecular Weight | 324.29 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 4 |
Related Mebendazole Standards
- Mebendazole EP Impurity E (CAS 31430-19-0)
- Mebendazole EP Impurity F (CAS 31545-31-0)
- Mebendazole EP Impurity D (CAS 132119-11-0)
- Mebendazole D3 (CAS 1173021-87-8)
- Mebendazole Impurity 14 (CAS 104663-13-0)
- Mebendazole (CAS 31431-39-7)
- Mebendazole EP Impurity C (CAS 66066-76-0)
- Mebendazole EP Impurity B (CAS 21472-33-3)
Recommended Standards
- Iguratimod Impurity 120 (CAS CATO-C4X-1826120)
- Furaltadone (CAS 139-91-3)
- Entacapone Impurity 10 (CAS CATO-C4X-162910)
- FA-Asp-Ala-OH (CAS 196791-00-1)
- Bexagliflozin Impurity 11 (CAS CATO-C4X-332211)
- Indometacin Impurity 65 (CAS CATO-C4X-147065)
- Isavuconazole Impurity 103 (CAS CATO-C4X-1236103)
- Methyl dimethylglycinate hydrochloride (CAS 1954-58-1)
- 2-[4-(4-Chlorophenyl)-2-methyl-3-oxo-1,2,4-oxadiazolidin-5-yl]-N-(2-methyl-4-nitrophenyl)acetamide (CAS 478077-80-4)
- 4,4'-Dibromo-4''-tert-butyltriphenylamine (CAS 852534-22-6)
- Ethyl 3,5-dimethylisoxazole-4-carboxylate (CAS 17147-42-1)
- 4-(3-Amino-4-chlorophenyl)-N,N-dimethylthiazol-2-amine (CAS 1443290-26-3)
- 4-(2-Methoxy-5-methylphenyl)-5-(thiophen-2-yl)-4h-1,2,4-triazole-3-thiol (CAS 379728-85-5)
- Peptide Impurity 04 (CAS 2913424-91-4)
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