Nifekalant impurity 2 CAS CATO-C4X-27972
| CAS No. | CATO-C4X-27972 |
| Molecular Formula | C13H15N3O4S |
| Molecular Weight | 309.34 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Nifekalant impurity 2 (CAS CATO-C4X-27972, C13H15N3O4S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Nifekalant impurity 2 (C13H15N3O4S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H15N3O4S |
| Molecular Weight | 309.34 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Nifekalant Standards
- Nifekalant impurity 3 (CAS CATO-C4X-27973)
- Nifekalant Impurity 12 (CAS CATO-C4X-279712)
- Nifekalant Impurity 16 (CAS CATO-C4X-279716)
- Nifekalant impurity 5 (CAS CATO-C4X-27975)
- Nifekalant Impurity 9 (CAS CATO-C4X-27979)
- Nifekalant impurity 6 (CAS CATO-C4X-27976)
- Nifekalant Impurity 11 (CAS CATO-C4X-279711)
- Nifekalant impurity 7 (CAS CATO-C4X-27977)
Recommended Standards
- Vonoprazan Fumarate Impurity 12 (CAS CATO-C4X-102012)
- N-(Benzo[c][1,2,5]thiadiazol-4-yl)-2-methylimidazo[1,2-a]pyridine-3-carboxamide (CAS 1207009-42-4)
- 77171-24-5 Desulfoprogoitrin (CAS 77171-24-5)
- Benzyl (4-(difluoromethyl)bicyclo[2.2.2]octan-1-yl)carbamate (CAS 1252672-41-5)
- Ribavirin EP Impurity G (CAS 39030-43-8)
- Toceranib Impurity 3 (CAS CATO-C4X-25853)
- Epinephrine Impurity 78 (CAS CATO-C4X-184978)
- 3-[benzyl(methyl)amino]propan-1-ol (CAS 5814-42-6)
- 1-Ethyl-2-pyrrolidin-2-yl-1H-benzimidazoledihydrochloride (CAS 1332530-95-6)
- 3-Phenyl-5-(trifluoromethyl)isoxazole (CAS 62847-60-3)
- 4-Methyl-2-(p-tolyl)pyrimidine (CAS 79382-86-8)
- 7-(4-Methoxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazine-3,8(2H,7H)-dione (CAS 1031577-95-3)
- 4-(2,3-Difluorophenyl)-4-oxobutyric acid (CAS 898766-11-5)
- Semaglutide impurity 266 (CAS CATO-C4X-2226266)
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