Luliconazole impurity 27 CAS CATO-C4X-285327
| CAS No. | CATO-C4X-285327 |
| Molecular Formula | C12H8Cl2N2OS2 |
| Molecular Weight | 331.24 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Luliconazole impurity 27 (C12H8Cl2N2OS2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a process- or degradation-related impurity, Luliconazole impurity 27 (CAS CATO-C4X-285327, C12H8Cl2N2OS2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H8Cl2N2OS2 |
| Molecular Weight | 331.24 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related Luliconazole Standards
- Luliconazole impurity 25 (CAS CATO-C4X-285325)
- Luliconazole impurity 26 (CAS CATO-C4X-285326)
- Luliconazole impurity 28 (CAS CATO-C4X-285328)
- Luliconazole impurity 29 (CAS CATO-C4X-285329)
- Luliconazole impurity 30 (CAS CATO-C4X-285330)
- Luliconazole Impurity 4 (CAS CATO-C4X-28534)
- Luliconazole (CAS 187164-19-8)
- Luliconazole Impurity 15 (CAS CATO-C4X-285315)
Recommended Standards
- Ym 872 (CAS 210245-80-0)
- Tert-butyl 4-(3,5-dichlorophenyl)piperazine-1-carboxylate (CAS 951626-82-7)
- 1-Benzyl-3-(2-bromophenyl)piperazine (CAS 1248907-40-5)
- tert-Butyl 3-(2,6-dichlorophenyl)piperazine-1-carboxylate (CAS 886769-22-8)
- Diazoxide impurity 5 (CAS 19185-77-4)
- Carbetocin Impurity 5 (CAS CATO-C4X-19115)
- Gentamycin Sulfate EP Impurity C (Gentamicin B1) (CAS 36889-16-4)
- 1-(4-Chloropyridin-2-yl)thiourea (CAS 1824186-34-6)
- 5-[(Benzenesulfonyl)methyl]-3-phenyl-1,2-oxazole (CAS 106808-15-5)
- Hexahydroequilenin (CAS 517-07-7)
- Parecoxib Impurity 60 (CAS CATO-C4X-159160)
- N-(4-Chlorobenzyl)piperidin-3-amine hydrochloride (CAS 1261232-05-6)
- 3,4-Dibromo-1-cyclopropyl-1H-pyrrol-2(5H)-one (CAS 1706451-17-3)
- Des-Pro36-37-Tirzepatide (CAS CATO-CPTD788938)
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