Finerenone Impurity 220 CAS CATO-C4X-2880220
| CAS No. | CATO-C4X-2880220 |
| Molecular Formula | C18H15N3O2 |
| Molecular Weight | 305.33 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Finerenone Impurity 220 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Finerenone Impurity 220 (CAS CATO-C4X-2880220, C18H15N3O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Finerenone Impurity 220 (C18H15N3O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C18H15N3O2 |
| Molecular Weight | 305.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 3 |
Related Finerenone Standards
- Finerenone Impurity 186 (CAS CATO-C4X-2880186)
- Finerenone Impurity 83 (CAS CATO-C4X-288083)
- Finerenone Impurity 108 (CAS CATO-C4X-2880108)
- Finerenone Impurity 105 (CAS CATO-C4X-2880105)
- Finerenone Impurity 119（E-Isomer） (CAS 1870824-79-5)
- Finerenone Impurity 156 (CAS CATO-C4X-2880156)
- Finerenone Impurity 161 (CAS CATO-C4X-2880161)
- Finerenone Impurity 50(Mixture of Z and E Isomers) (CAS 1050477-39-8)
Recommended Standards
- Salcaprozate Impurity 4 (CAS CATO-C4X-25074)
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- Pirimiphos-Methyl (CAS 29232-93-7)
- Fluvoxamine Impurity 15 (CAS 61718-83-0)
- Empagliflozin Impurity 137 (CAS CATO-C4X-1065137)
- Benzbromarone Impurity 27 (CAS CATO-C4X-225027)
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