Abrocitinib Impurity 49 CAS CATO-C4X-288449
| CAS No. | CATO-C4X-288449 |
| Molecular Formula | C19H20ClN5O2 |
| Molecular Weight | 385.85 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Abrocitinib Impurity 49 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Abrocitinib Impurity 49 (CAS CATO-C4X-288449) is a certified pharmaceutical impurity reference standard with the molecular formula C19H20ClN5O2 and a molecular weight of 385.85 g/mol.
Based on its molecular formula C19H20ClN5O2, Abrocitinib Impurity 49 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 385.85 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C19H20ClN5O2 |
| Molecular Weight | 385.85 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related Abrocitinib Standards
- Abrocitinib Impurity 24 (CAS 1622981-01-4)
- Abrocitinib Impurity 39 (CAS CATO-C4X-288439)
- Abrocitinib Nitroso Impurity 9 (CAS CATO-C4X-28849)
- Abrocitinib Impurity 36 (CAS CATO-C4X-288436)
- Abrocitinib Nitroso Impurity 10 (CAS CATO-C4X-288410)
- Abrocitinib Impurity 52 (CAS CATO-C4X-288452)
- Abrocitinib Impurity 54 (CAS CATO-C4X-288454)
- Abrocitinib Impurity 56 (CAS 1208319-36-1)
Recommended Standards
- Lornoxicam impurity 87 (CAS CATO-C4X-201687)
- N-{4-[(4-chlorobenzenesulfonyl)methyl]phenyl}benzamide (CAS 1354448-67-1)
- Lornoxicam impurity 63 (CAS CATO-C4X-201663)
- (4-((3-Chlorophenoxy)methyl)-2-nitrophenyl)(p-tolyl)sulfane (CAS 477869-60-6)
- Modafinil EP Impurity A (CAS 63547-24-0)
- Telmisartan Impurity 10 (CAS 136304-93-3)
- Everolimus Impurity 25 (CAS CATO-C4X-112225)
- 2-(2-(4-Methylpiperidin-1-yl)-2-oxoethyl)-1H-benzo[de]isoquinoline-1,3(2H)-dione (CAS 326907-64-6)
- (2-Ethoxy-5-fluoropyridin-4-yl)methanol (CAS 1809158-12-0)
- 2,2,2-Trifluoro-N-phenylethanecarbonimidoyl chloride (CAS 1537905-51-3)
- N-methoxy-N-methyltetrahydro-2H-thiopyran-4-carboxamide (CAS 887481-46-1)
- Capivasertib Impurity 17 (CAS CATO-C4X-331217)
- tert-Butyl (4-(2-amino-N-cyclopropylacetamido)cyclohexyl)carbamate (CAS 1353971-92-2)
- Semaglutide impurity 47 (CAS CATO-C4X-222647)
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