Phosphoramidite Impurity 26 CAS CATO-C4X-288626
| CAS No. | CATO-C4X-288626 |
| Molecular Formula | C21H34N5O7P |
| Molecular Weight | 499.50 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Phosphoramidite Impurity 26 (CAS CATO-C4X-288626), a pharmacopoeial impurity reference standard (molecular formula C21H34N5O7P, MW 499.50 g/mol) used for the identification and quantification of trace impurities in APIs.
Phosphoramidite Impurity 26 (C21H34N5O7P) contains a flavonoid core, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H34N5O7P |
| Molecular Weight | 499.50 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 5 |
Related Phosphoramidite Standards
Recommended Standards
- Naltrexone impurity 46 (CAS CATO-C4X-147546)
- (1S,3S,5S)-1,3,5-Tris(4-nitrophenyl)adamantane (CAS 1298062-83-5)
- Naltrexone impurity 40 (CAS CATO-C4X-147540)
- (8S)-1-(1,1-dimethylethyl) 10-(9H-fluoren-9-ylmethyl) ester, 8-carboxy-5-oxo-3-oxa-2,6,9-triazadecanedioic acid (CAS 600153-12-6)
- Ozenoxacin Impurity 55 (CAS CATO-C4X-279655)
- Ensifentrine impurity (CAS 4359-64-2)
- Levamisole EP Impurity A (CAS 32190-34-4)
- tert-Butyl 4-((4-(hydroxymethyl)benzyl)oxy)piperidine-1-carboxylate (CAS 937796-03-7)
- 1,4-Dibutyl Benzene-1,4-dicarboxylate (CAS 1962-75-0)
- 2-Oxoindoline-7-carboxylic Acid (CAS 25369-43-1)
- (1-(Pyrimidin-4-yl)azetidin-3-yl)methanol (CAS 1484880-44-5)
- 3-(Difluoromethyl)aniline hydrochloride (CAS 161363-34-4)
- N-(4-chlorophenyl)-2-((5-(4-chlorophenyl)-4-(p-tolyl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 443738-36-1)
- Acetyl Tetrapeptide-5 (CAS 820959-17-9)
Why CATO?
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