Velpatasvir Impurity 5 CAS CATO-C4X-28945
| CAS No. | CATO-C4X-28945 |
| Molecular Formula | C47H52N8O6 |
| Molecular Weight | 824.97 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Velpatasvir Impurity 5 (CAS CATO-C4X-28945, C47H52N8O6) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Velpatasvir Impurity 5 (C47H52N8O6) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Velpatasvir Impurity 5 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C47H52N8O6 |
| Molecular Weight | 824.97 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 26.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 8 |
Related Velpatasvir Standards
- Velpatasvir Impurity 1 (CAS CATO-C4X-28941)
- Velpatasvir Impurity 12 (CAS CATO-C4X-289412)
- Velpatasvir Impurity 4 (CAS CATO-C4X-28944)
- Velpatasvir Impurity 2 (CAS 1378391-45-7)
- Velpatasvir (CAS 1377049-84-7)
- Velpatasvir Impurity 11 (CAS CATO-C4X-289411)
- Velpatasvir Impurity 3 (CAS 1493768-22-1)
- Velpatasvir D3 (CAS 2172676-06-9)
Recommended Standards
- 2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53-Octadecaoxapentapentacontan-55-ol (CAS 171286-86-5)
- Nodularin (CAS 118399-22-7)
- 1,1'-(Propane-1,3-diylbis(4,1-phenylene))diethanone (CAS 6337-58-2)
- Semaglutide impurity 93 (CAS CATO-C4X-222693)
- Tazobactam EP Impurity B (CAS 120701-87-3)
- Osimertinib Impurity 116 (CAS CATO-C4X-2045116)
- AZD-9291 Impurity 6 (CAS CATO-C4X-11276)
- cis-4-Hydroxypiperidine-3-carboxylic acid (CAS 71609-37-5)
- N-(2-Cyano-3-methylbutan-2-yl)-2-((4-(4-ethoxyphenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 782464-96-4)
- 1-methoxy-2-methylnaphthalene (CAS 14093-86-8)
- N-(3-Bromo-4-methoxybenzyl)-3-pentanamine hydrobromide (CAS 1609407-30-8)
- 2-(2,6-Difluoro-4-nitrophenyl)acetonitrile (CAS 1280739-81-2)
- 5-Bromo-4-fluoro-2-methylbenzonitrile (CAS 1695413-38-7)
- D-Gln19-Tirzepatide (CAS CATO-CPTD788915)
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