Letermovir Impurity 8 CAS CATO-C4X-29158
| CAS No. | CATO-C4X-29158 |
| Molecular Formula | C29H28F4N4O4 |
| Molecular Weight | 572.55 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Letermovir Impurity 8 (CAS CATO-C4X-29158, C29H28F4N4O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Letermovir Impurity 8 (C29H28F4N4O4) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 16.0, corresponding to approximately 16 ring(s) or double-bond equivalent(s). With a molecular weight of 572.55 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Letermovir Impurity 8 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C29H28F4N4O4 |
| Molecular Weight | 572.55 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Letermovir Standards
- rac-Letermovir, >98% (CAS 791116-51-3)
- Letermovir (CAS 917389-32-3)
- Letermovir Impurity 10 (CAS CATO-C4X-291510)
- Letermovir Impurity 103 (CAS CATO-C4X-2915103)
- Letermovir Impurity 19 (CAS CATO-C4X-291519)
- Letermovir Impurity 42 (CAS CATO-C4X-291542)
- Letermovir Impurity 44 (CAS CATO-C4X-291544)
- Letermovir Impurity 47 (CAS CATO-C4X-291547)
Recommended Standards
- Letermovir Impurity 70 (CAS CATO-C4X-291570)
- Letermovir Impurity 84 (CAS CATO-C4X-291584)
- Letermovir Impurity 67 (CAS CATO-C4X-291567)
- Letermovir Impurity 9 (CAS CATO-C4X-29159)
- Ramosetron Impurity 24 (CAS CATO-C4X-118224)
- Oseltamivir Impurity 88 (CAS CATO-C4X-172088)
- Xanomeline Impurity 12 (CAS CATO-C4X-330112)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com