Probucol Impurity 18 CAS CATO-C4X-292018
| CAS No. | CATO-C4X-292018 |
| Molecular Formula | C31H48O4S2 |
| Molecular Weight | 548.84 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Probucol Impurity 18 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Probucol Impurity 18 (CAS CATO-C4X-292018, C31H48O4S2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Probucol Impurity 18 (C31H48O4S2) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C31H48O4S2 |
| Molecular Weight | 548.84 g/mol |
| Purity | 95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Sulfur Atoms | 2 |
Related Probucol Standards
- Probucol Impurity 19 (CAS CATO-C4X-292019)
- Probucol Impurity 22 (CAS CATO-C4X-292022)
- Probucol Impurity 4 (CAS CATO-C4X-29204)
- Probucol Impurity 14 (CAS 31121-17-2)
- Probucol Impurity 2 (CAS CATO-C4X-29202)
- Probucol Impurity 3 (CAS CATO-C4X-29203)
- Probucol-propionyl-<SUP>13</SUP>C<SUB>3</SUB> (CAS 1173019-29-8)
- Probucol Impurity 12 (CAS 186503-04-8)
Recommended Standards
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- Edaravone Impurity 2 (CAS 100-63-0)
- Ozagrel Impurity 1 (CAS CATO-C4X-19711)
- Lemborexant Impurity 82 (CAS CATO-C4X-304282)
- N1-(3-Aminopropyl)-N1,N3,N3-trimethylpropane-1,3-diamine (CAS 19475-35-5)
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- tert-Butyl benzyl((2,5-dioxopyrrolidin-3-yl)methyl)carbamate (CAS 1799421-07-0)
- Apremilast impurity 90 (CAS CATO-C4X-100990)
- 4-Bromo-2-ethoxypyrimidine (CAS 959240-78-9)
- Vancomycin Hexapeptide (CAS 115236-65-2)
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