Probucol Impurity 9 CAS CATO-C4X-29209
| CAS No. | CATO-C4X-29209 |
| Molecular Formula | C14H22O3S |
| Molecular Weight | 270.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Probucol Impurity 9.
Probucol Impurity 9 (CAS CATO-C4X-29209) is a certified pharmaceutical impurity reference standard with the molecular formula C14H22O3S and a molecular weight of 270.39 g/mol.
The molecular framework of Probucol Impurity 9 (C14H22O3S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Probucol Impurity 9 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H22O3S |
| Molecular Weight | 270.39 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Sulfur Atoms | 1 |
Related Probucol Standards
- Probucol Impurity 10 (CAS 3957-71-9)
- Probucol Impurity 23 (CAS CATO-C4X-292023)
- Probucol Impurity 21 (CAS CATO-C4X-292021)
- Probucol Impurity 1 (CAS 950-59-4)
- Probucol Impurity 6 (CAS CATO-C4X-29206)
- Probucol Impurity 20 (CAS CATO-C4X-292020)
- Probucol Impurity 13 (CAS 40084-31-9)
- Probucol Impurity 17 (CAS 1195639-22-5)
Recommended Standards
- Piperazine Impurity 4 (CAS 1293489-64-1)
- Heptyl p-Toluenesulfonate (CAS 24767-82-6)
- Promethazine EP Impurity C (CAS 37707-23-6)
- Cadusafos (CAS 95465-99-9)
- Rupatadine impurity 12 (CAS CATO-C4X-102712)
- Ilaprazole Impurity 100 (CAS CATO-C4X-1130100)
- Loxoprofen impurity 87 (CAS CATO-C4X-148887)
- 2-(4-hydroxypiperidin-1-yl)-N,N-dimethylacetamide (CAS 1152845-38-9)
- (2-Chloropyridin-4-yl)(3-(hydroxymethyl)piperidin-1-yl)methanone (CAS 1156800-32-6)
- (cyclopropylmethyl)(prop-2-en-1-yl)amine (CAS 36178-62-8)
- (R)-3-Aminooxetan-2-one 4-methylbenzenesulfonate (CAS 149572-97-4)
- Methyl 1-(furan-2-ylmethyl)-5-hydroxy-2-methyl-1H-indole-3-carboxylate (CAS 443647-93-6)
- 5-Ethyl-2-(oxiran-2-yl)pyridine (CAS 471295-97-3)
- Semaglutide-d15 (CAS 910463-68-2(non-labelled))
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