Lemborexant Impurity 60 CAS CATO-C4X-304260
| CAS No. | CATO-C4X-304260 |
| Molecular Formula | C19H18FNO5 |
| Molecular Weight | 359.35 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 359.35 g/mol gives Lemborexant Impurity 60 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Lemborexant Impurity 60 (CAS CATO-C4X-304260, C19H18FNO5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C19H18FNO5, Lemborexant Impurity 60 contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 359.35 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Lemborexant Impurity 60 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H18FNO5 |
| Molecular Weight | 359.35 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Lemborexant Standards
- Lemborexant Impurity 24 (CAS CATO-C4X-304224)
- Lemborexant Impurity 47 (CAS CATO-C4X-304247)
- Lemborexant Impurity 74 (CAS CATO-C4X-304274)
- Lemborexant Impurity 101 (CAS CATO-C4X-3042101)
- Lemborexant Impurity 25 (CAS CATO-C4X-304225)
- Lemborexant Impurity 43 (CAS CATO-C4X-304243)
- Lemborexant Impurity 108 (CAS CATO-C4X-3042108)
- Lemborexant Impurity 109 (CAS CATO-C4X-3042109)
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