N-Nitroso Fedratinib Impurity 3 CAS CATO-C4X-30883
| CAS No. | CATO-C4X-30883 |
| Molecular Formula | C23H26N8O5S |
| Molecular Weight | 526.57 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
N-Nitroso Fedratinib Impurity 3 (CAS CATO-C4X-30883) is a certified pharmaceutical impurity reference standard with the molecular formula C23H26N8O5S and a molecular weight of 526.57 g/mol.
The molecular framework of N-Nitroso Fedratinib Impurity 3 (C23H26N8O5S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), N-Nitroso Fedratinib Impurity 3 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H26N8O5S |
| Molecular Weight | 526.57 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 8 |
| Sulfur Atoms | 1 |
Related N Standards
- N-Nitroso Moexipril (CAS 1026879-47-9)
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Recommended Standards
- TERRITREM B (CAS 70407-20-4)
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- (7,7-Dimethyl-6,8-dioxa-2-azaspiro[3.5]nonan-2-yl)(4-methyl-1,2,3-thiadiazol-5-yl)methanone (CAS 1396717-68-2)
- 17beta-(Trimethylsiloxy)testosterone (CAS 5055-42-5)
- 5-(2,3-Difluorophenyl)pyrazin-2-amine (CAS 1489671-37-5)
- 3,4-Dibromo-3-chlorotetrahydrothiophene 1,1-dioxide (CAS 119885-07-3)
- N1,N1-Bis(2-(phenylthio)ethyl)oxalamide (CAS 191980-39-9)
- 1-(Pyrrolidin-1-yl)cyclopropanecarbonitrile (CAS 387845-43-4)
- Semaglutide impurity 290 (CAS CATO-C4X-2226290)
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