Vazegepant Impurity 4 CAS CATO-C4X-32004
| CAS No. | CATO-C4X-32004 |
| Molecular Formula | C36H46N8O3 |
| Molecular Weight | 638.80 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Vazegepant Impurity 4 (CAS CATO-C4X-32004), a pharmacopoeial impurity reference standard (molecular formula C36H46N8O3, MW 638.80 g/mol) used for the identification and quantification of trace impurities in APIs.
Vazegepant Impurity 4 (C36H46N8O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C36H46N8O3 |
| Molecular Weight | 638.80 g/mol |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 8 |
Related Vazegepant Standards
- Vazegepant (CAS 1337918-83-8)
- Vazegepant Impurity 7 (CAS CATO-C4X-32007)
- Vazegepant Impurity 5 (CAS CATO-C4X-32005)
- Vazegepant Impurity 13 (CAS CATO-C4X-320013)
- Vazegepant Impurity 19 (CAS 2923756-41-4)
- Vazegepant Impurity 18 (CAS CATO-C4X-320018)
- Vazegepant Impurity 23 (CAS CATO-C4X-320023)
- Vazegepant Impurity 31 (CAS CATO-C4X-320031)
Recommended Standards
- Epalrestat Impurity 5 (CAS CATO-C4X-22365)
- Epalrestat impurity 49 (CAS CATO-C4X-223649)
- Biotin-PEG8-amine (CAS 2183447-27-8)
- Peramivir Impurity 78 (CAS CATO-C4X-183378)
- Ilaprazole impurity 203 (CAS 1378653-43-0（free base）)
- Lidocaine Impurity 33 (CAS 1374010-02-2)
- Semaglutide Impurity 184 (CAS CATO-C4X-2226184)
- 4-Methyl-N-(2-(3-methylisoxazol-5-yl)ethyl)-2-(1H-pyrrol-1-yl)thiazole-5-carboxamide (CAS 1421472-50-5)
- Ampicillin Impurity 93 (CAS CATO-C4X-144393)
- 2-(Bromomethyl)-5-chlorobenzo[b]thiophene (CAS 99592-53-7)
- 4-Amino-6-(aminomethyl)-5-(difluoromethyl)picolinic acid (CAS 1804722-08-4)
- Tert-butyl 8-amino-8-methyl-3-azabicyclo[3.2.1]Octane-3-carboxylate (CAS 2375195-91-6)
- 1,6-DImethyl-1h-pyrazolo[3,4-b]pyridin-3-amine (CAS 1082942-26-4)
- Semaglutide impurity 51 (CAS CATO-C4X-222651)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com