Allisartan Isoproxil Impurity 8 CAS CATO-C4X-32178
| CAS No. | CATO-C4X-32178 |
| Molecular Formula | C7H10BrClN2 |
| Molecular Weight | 237.52 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Allisartan Isoproxil Impurity 8 is closely related to a nitrile group, chlorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Allisartan Isoproxil Impurity 8 (CAS CATO-C4X-32178) is a certified pharmaceutical impurity reference standard with the molecular formula C7H10BrClN2 and a molecular weight of 237.52 g/mol.
Based on its molecular formula C7H10BrClN2, Allisartan Isoproxil Impurity 8 contains a nitrile group, chlorine/bromine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 237.52 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Allisartan Isoproxil Impurity 8 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H10BrClN2 |
| Molecular Weight | 237.52 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 2 |
Related Allisartan Standards
- Allisartan Isoproxil Impurity 7 (CAS CATO-C4X-32177)
- Allisartan Isoproxil Impurity 6 (CAS CATO-C4X-32176)
- Allisartan Isoproxil Impurity 1 (CAS CATO-C4X-32171)
- Allisartan Isoproxil Impurity 24 (CAS CATO-C4X-321724)
- Allisartan Isoproxil Impurity 13 (CAS CATO-C4X-321713)
- Allisartan Isoproxil Impurity 2 (CAS CATO-C4X-32172)
- Allisartan Isoproxil Impurity 32 (CAS CATO-C4X-321732)
- Allisartan Isoproxil Impurity 31 (CAS CATO-C4X-321731)
Recommended Standards
- 4-Bromo-5-chloro-3-methyl-1-propyl-1H-pyrazole (CAS 29939-07-9)
- 2-(2,2-dichlorocyclopropyl)ethane-1-sulfonyl chloride (CAS 1909317-56-1)
- 1-(4-bromobutyl)-4-chloro-1H-pyrazole (CAS 132449-90-2)
- 1-Bromo-3-chloro-4-(methylthio)benzene (CAS 101084-82-6)
- Solifenacin Impurity 26 (CAS CATO-C4X-105326)
- Duloxetine Impurity 34 (CAS CATO-C4X-133634)
- Dienogest EP Impurity E (CAS 102193-41-9)
- H-Glu-Glu-Leu-OH (H-1924.0250) (CAS 189080-99-7)
- N-(azetidin-3-yl)-N-methylisobutyramide (CAS 1487875-17-1)
- Methyl 2-{3-[4-(benzyloxy)phenyl]phenyl}acetate (CAS 1820651-02-2)
- Bromhexine Impurity 10 (CAS 2512203-87-9)
- 2,2-Dimethyl-2-fluoropropiophenone (CAS 560085-36-1)
- 2,6-Diaminopyridin-4-ol (CAS 99845-76-8)
- Crustacean Cardioactive Peptide (CAS 107090-96-0)
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