Ledipasvir Impurity 45 CAS CATO-C4X-331345
| CAS No. | CATO-C4X-331345 |
| Molecular Formula | C35H32N6O |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Ledipasvir Impurity 45 (CAS CATO-C4X-331345), a pharmacopoeial impurity reference standard (molecular formula C35H32N6OHCl, MW 589.14 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Ledipasvir Impurity 45 (C35H32N6OHCl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 22.0, corresponding to approximately 22 ring(s) or double-bond equivalent(s). With a molecular weight of 589.14 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C35H32N6O HCl |
| Molecular Weight | 589.14 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 22.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 6 |
Related Ledipasvir Standards
- Ledipasvir Impurity-3 (CAS 1256388-50-7)
- Ledipasvir (CAS 1256388-51-8)
- Ledipasvir Intermediate (CAS 1256393-27-7)
- Ledipasvir impurity 1 (CAS 134877-62-6)
- Ledipasvir Impurity 7 (CAS 1441670-89-8)
- Ledipasvir Acetone (CAS 1441674-54-9)
- Ledipasvir Impurity 8 (CAS 1499193-65-5)
- Ledipasvir D-tartrate (CAS 1502654-87-6)
Recommended Standards
- Brivaracetam Impurity 3 (CAS 357336-99-3)
- Ceftazidime Impurity 102 (CAS CATO-C4X-1212102)
- Mesalazine EP Impurity D (CAS 99-05-8)
- 3-(Trifluoromethyl)piperidin-4-amine dihydrochloride (CAS 1356342-57-8)
- Riboflavin Impurity 26 (CAS CATO-C4X-181926)
- 5-[(4-Methoxyphenyl)methyl]-4-sulfanylidene-8-thia-3,5,10-triazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),10,12-tetraen-6-one (CAS 1019151-39-3)
- D-Alanyl-L-proline (CAS 61430-12-4)
- N-((1-(Thiophen-2-yl)cyclopropyl)methyl)-2,3-dihydrobenzo[b][1,4]dioxine-6-sulfonamide (CAS 1207007-28-0)
- 3-Iodo-6-methyl-4H-chromen-4-one (CAS 341528-94-7)
- D-γ-Glu20-Side-Tirzepatide (CAS CATO-CPTD788929)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com