FCN437 Impurity 9 CAS CATO-C4X-33249
| CAS No. | CATO-C4X-33249 |
| Molecular Formula | C18H25N2O4 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
FCN437 Impurity 9 (C18H25N2O4Br) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, FCN437 Impurity 9 (CAS CATO-C4X-33249, C18H25N2O4Br) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H25N2O4 Br |
| Molecular Weight | 413.31 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- Baloxavir Impurity 114 (CAS CATO-C4X-2108114)
- Esomeprazole Impurity 115 (CAS 1424857-83-9)
- N-Nitroso Clozapine EP Impurity A (CAS 90353-66-5)
- 3-Chloro-2,5-difluorobenzaldehyde (CAS 1261884-40-5)
- 6-Bromo-N-cyclopentylpicolinamide (CAS 1209459-00-6)
- 7-Chloro-2-(5-chloro-2-thienyl)-8-methylquinoline-4-carbonyl chloride (CAS 1160256-94-9)
- 1-(3-(Benzo[d]thiazol-2-yloxy)azetidin-1-yl)-3-phenylpropan-1-one (CAS 1421455-37-9)
- (4-Chloro-2-methylfuran-3-yl)(phenyl)methanol (CAS 1443326-92-8)
- 2-Ethylhexyl sulfate sodium salt (CAS 126-92-1)
- Semaglutide Impurity 138 (CAS CATO-C4X-2226138)
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