Atrasentan Impurity 202 CAS CATO-C4X-3347202

Purity 95%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-3347202
Molecular FormulaC29H38N2O6
Molecular Weight510.62 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Atrasentan Impurity 202 CAS CATO-C4X-3347202 chemical structure

Description

The occurrence of Atrasentan Impurity 202 is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies Atrasentan Impurity 202 (CAS CATO-C4X-3347202), a pharmacopoeial impurity reference standard (molecular formula C29H38N2O6, MW 510.62 g/mol) used for the identification and quantification of trace impurities in APIs.

Atrasentan Impurity 202 (C29H38N2O6) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC29H38N2O6
Molecular Weight510.62 g/mol
AppearancePale yellow to yellow crystalline powder
Purity95%
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)12.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Nitrogen Atoms2

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