Nerandomilast impurity 16 CAS CATO-C4X-347316
| CAS No. | CATO-C4X-347316 |
| Molecular Formula | C11H14ClN3OS |
| Molecular Weight | 271.77 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Nerandomilast impurity 16 (CAS CATO-C4X-347316), a pharmacopoeial impurity reference standard (molecular formula C11H14ClN3OS, MW 271.77 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C11H14ClN3OS, Nerandomilast impurity 16 contains a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 271.77 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H14ClN3OS |
| Molecular Weight | 271.77 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Nerandomilast Standards
- Nerandomilast impurity 19 (CAS CATO-C4X-347319)
- Nerandomilast impurity 18 (CAS CATO-C4X-347318)
- Nerandomilast impurity 21 (CAS CATO-C4X-347321)
- Nerandomilast Impurity 34 (CAS CATO-C4X-347334)
- Nerandomilast impurity 5 (CAS CATO-C4X-34735)
- Nerandomilast impurity 22 (CAS CATO-C4X-347322)
- Nerandomilast impurity 23 (CAS CATO-C4X-347323)
- Nerandomilast impurity 11 (CAS CATO-C4X-347311)
Recommended Standards
- 1-(4-Chlorophenyl)-3-morpholinothiourea (CAS 455302-65-5)
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- Sertraline - Impurity C (Freebase) (CAS 107538-91-0)
- 2-Chloro-N-cyclopropyl-N-((3-(methylthio)pyrazin-2-yl)methyl)acetamide (CAS 1353978-90-1)
- Uridine Impurity 10 Disodium Salt (CAS 91183-98-1)
- Montelukast EP Impurity C(Mixture of Diastereomers) (CAS 909849-96-3)
- Upadacitinib Impurity 3 (CAS CATO-C4X-24053)
- 4,4',4'',4'''-([2,2'-Bi(1,3-dithiolylidene)]-4,4',5,5'-tetrayl)tetrabenzaldehyde (CAS 1639134-02-3)
- 1-(2-Methylbutanoyl)piperidine-3-carboxylic acid (CAS 954584-11-3)
- 4-Chloro-5-propyl-1H-pyrazol-3-amine (CAS 110580-34-2)
- Methyl 5-(morpholinomethyl)-6-phenylpicolinate (CAS 1152095-54-9)
- (11aR)-10,11,12,13-Tetrahydro-N,N,3,7-tetramethyl-diindeno[7,1-de:1',7'-fg][1,3,2]dioxaphosphocin-5-amine (CAS 930784-57-9)
- Methyl 6-Amino-5-nitropyridine-2-carboxylate (CAS 538372-32-6)
- Allo-D-Ile27-Tirzepatide (CAS CATO-CPTD788961)
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