Nerandomilast Impurity 36 CAS CATO-C4X-347336
| CAS No. | CATO-C4X-347336 |
| Molecular Formula | C15H15Cl2N5S |
| Molecular Weight | 368.28 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Nerandomilast Impurity 36 (CAS CATO-C4X-347336), a pharmacopoeial impurity reference standard (molecular formula C15H15Cl2N5S, MW 368.28 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution, Nerandomilast Impurity 36 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 368.28 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H15Cl2N5S |
| Molecular Weight | 368.28 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Nerandomilast Standards
- Nerandomilast Impurity 33 (CAS CATO-C4X-347333)
- Nerandomilast impurity 25 (CAS CATO-C4X-347325)
- Nerandomilast impurity 24 (CAS CATO-C4X-347324)
- Nerandomilast impurity 30 (CAS CATO-C4X-347330)
- Nerandomilast Impurity 35 (CAS CATO-C4X-347335)
- Nerandomilast impurity 2 (CAS CATO-C4X-34732)
- Nerandomilast impurity 9 (CAS CATO-C4X-34739)
- Nerandomilast impurity 8 (CAS CATO-C4X-34738)
Recommended Standards
- N-Benzyl-2-bromo-N-isopropylbenzenesulfonamide (CAS 1183134-13-5)
- N-(2,6-Dichlorophenyl)-4-(pyrazin-2-yl)piperazine-1-carbothioamide (CAS 89007-43-2)
- 4-Bromo-N-(1-methylethyl)-N-(phenylmethyl)-Benzenesulfonamide (CAS 1184422-06-7)
- 1-(2,4-Bis(trifluoromethyl)benzyl)-1H-indole-4-carbonitrile (CAS 1956356-16-3)
- Urapidil Impurity 5 (CAS 34661-73-9)
- Bifonazole Impurity 12 (CAS CATO-C4X-156012)
- Cefadroxil Impurity 40 (CAS 646536-87-0)
- 4-(1H-Indol-3-yl)-5-methyl-thiazol-2-ylamine hydrochloride (CAS 1197234-30-2)
- 2-(2-(4-Methoxyphenoxy)ethyl)isoindoline-1,3-dione (CAS 321432-17-1)
- Travoprost Impurity 50 (CAS 2218532-68-2)
- 2-(4-Ethoxyphenyl)ethanethioamide (CAS 1017022-22-8)
- 2-Chloro-N-cyclopropyl-N-[2-oxo-2-(1H-pyrrol-2-yl)-ethyl]-acetamide (CAS 1353989-44-2)
- 1-Methyl-7,8-dihydroimidazo[1,5-c]pyrimidin-5(6H)-one (CAS 51777-26-5)
- (Thr(PO3H2)231)-Tau Peptide (225-237) trifluoroacetate salt (CAS 1670270-09-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com