Linaprazan Impurity 5 CAS CATO-C4X-34865
| CAS No. | CATO-C4X-34865 |
| Molecular Formula | C22H27N3O2 |
| Molecular Weight | 365.47 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Linaprazan Impurity 5 is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Linaprazan Impurity 5 (CAS CATO-C4X-34865) is a certified pharmaceutical impurity reference standard with the molecular formula C22H27N3O2 and a molecular weight of 365.47 g/mol.
The molecular framework of Linaprazan Impurity 5 (C22H27N3O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H27N3O2 |
| Molecular Weight | 365.47 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 3 |
Related Linaprazan Standards
- Linaprazan (CAS 248919-64-4)
- Linaprazan Impurity 1 (CAS CATO-C4X-34861)
- Linaprazan Impurity 2 (CAS CATO-C4X-34862)
- Linaprazan Impurity 8 (CAS CATO-C4X-34868)
- Linaprazan Impurity 7 (CAS CATO-C4X-34867)
- Linaprazan Impurity 6 (CAS CATO-C4X-34866)
- Linaprazan Impurity 3 (CAS CATO-C4X-34863)
- Linaprazan Impurity 13 (CAS CATO-C4X-348613)
Recommended Standards
- Prednisone-d7 (Major) (CAS CATO-C4X-191926)
- 5-[[4-(2-Cyclohexylethoxy)-3-methoxyphenyl]methylene]-2,4-thiazolidinedione-d4 (CAS 1795143-97-3)
- Olopatadine lmpurity 60 (CAS CATO-C4X-171860)
- 4-Iodo-2-methyl-3-(trifluoromethoxy)pyridine-6-carbonyl chloride (CAS 1806233-78-2)
- Celecoxib Impurity 78 (CAS CATO-C4X-104378)
- Atomoxetine Impurity 53 (CAS CATO-C4X-155053)
- Moxidectin EP Impurity C (CAS 114041-23-5)
- 6-(Thiophen-3-yl)pyridazin-3-amine (CAS 105538-02-1)
- (E)-2,3-Dibromo-4-oxobut-2-enoic acid (CAS 90994-06-2)
- 1-((9H-fluoren-9-yl)methyl) 2-(tert-butyl) hydrazine-1,2-dicarboxylate (CAS 936015-89-3)
- Methyl 2-(4-bromo-1-methyl-1H-pyrazol-3-yl)acetate (CAS 2091858-06-7)
- 6-Chloro-N-methyl-2-benzothiazolamine (CAS 34551-19-4)
- 2-(1-Benzylpiperidin-4-yl)ethan-1-amine hydrochloride (CAS 86945-20-2)
- Biotinyl-S6 Phosphate Acceptor Peptide trifluoroacetate salt (CAS 1815618-12-2)
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