Ala-Gly-Cys-Lys-Ala(CN)-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH(disulfide bond) CAS CATO-CPTD788765
| CAS No. | CATO-CPTD788765 |
| Molecular Formula | C76H102N18O18S2 |
| Molecular Weight | 1619.86 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Ala-Gly-Cys-Lys-Ala(CN)-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH(disulfide bond) is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Ala-Gly-Cys-Lys-Ala(CN)-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH(disulfide bond) (CAS CATO-CPTD788765, C76H102N18O18S2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C76H102N18O18S2, Ala-Gly-Cys-Lys-Ala(CN)-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH(disulfide bond) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 1619.86 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C76H102N18O18S2 |
| Molecular Weight | 1619.86 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 35.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 18 |
| Sulfur Atoms | 2 |
Recommended Standards
- Somatostatin Impurity 5 X TFA Salt (CAS CATO-C4X-23505)
- Ala(CN)5-Somatostatin (CAS CATO-CPTD788780)
- Bombesin (CAS 31362-50-2)
- Spexin (CAS 1370290-58-6)
- Spermine Impurity 1 (CAS CATO-C4X-33931)
- Cefadroxil Impurity 19 (CAS CATO-C4X-122419)
- Empagliflozin Impurity 92 (CAS CATO-C4X-106592)
- 238743-29-8 N-[(3,4-Difluorophenyl)methylidene]hydroxylamine DTXSID80724873 (CAS 238743-29-8)
- Benzo[b]thiophene-5-carboximidamide hydrochloride (CAS 154650-75-6)
- N-(4-Bromo-2-nitrophenyl)-2-chloroacetamide (CAS 854583-85-0)
- 2-(Pyren-1-yl)-1,10-phenanthroline (CAS 197852-92-9)
- 2-(2-([1,1'-Biphenyl]-4-yl)oxazolidin-3-yl)ethanol (CAS 874198-35-3)
- 2-Methyl-5-((2-(piperidin-2-yl)ethyl)thio)-1,3,4-thiadiazole (CAS 1248361-79-6)
- Semaglutide Impurity 7 (CAS CATO-C4X-22267)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com