4-Nitrophenylhydrazine CAS 100-16-3
| CAS No. | 100-16-3 |
| Molecular Formula | C6H7N3O2 |
| Molecular Weight | 153.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Nitrophenylhydrazine.
4-Nitrophenylhydrazine (CAS 100-16-3), molecular formula C6H7N3O2 and molecular weight 153.14 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 4-Nitrophenylhydrazine (C6H7N3O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 153.14 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-Nitrophenylhydrazine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H7N3O2 |
| Molecular Weight | 153.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 3 |
Related Nitrophenylhydrazine Standards
- 3034-19-3 2-Nitrophenylhydrazine Hydrazine, (o-nitrophenyl)- 4-15-00-00304 (Beilstein Handbook Reference) BRN 0512797 EINECS 221-222-6 (CAS 3034-19-3)
- 5-Methyl-2-nitrophenylhydrazine (CAS 56637-42-4)
- 2-Nitrophenylhydrazine Hydrochloride (CAS 6293-87-4)
- 4-Nitrophenylhydrazine HCl (CAS 636-99-7)
- p-Nitrophenylhydrazine sulfate (CAS 58332-97-1)
- 3-Nitrophenylhydrazine Hydrochloride (CAS 636-95-3)
Recommended Standards
- Methyl 2-amino-3,3-difluoro-2-methylpropanoate (CAS 87492-65-7)
- 4-Amino-6-methoxypyrimidine-5-carbaldehyde (CAS 1004956-62-0)
- 6,7-Difluoro-1H-indole (CAS 271780-84-8)
- Methyl 2-vinyloxazole-4-carboxylate (CAS 1004996-51-3)
- 2-Propenoic acid, 2-methyl-, polymer with butyl 2-methyl-2-propenoate and butyl 2-propenoate (CAS 30231-49-3)
- 3,5-Difluoro-4-methoxyphenylboronic Acid (CAS 208641-98-9)
- (R)-(+)-1-(p-Tolyl)ethylamine (R)-(+)-4-(1-Aminoethyl)toluene 4187-38-6 T1380 (CAS 4187-38-6)
- Manidipine Hydrochloride Oxidant Body (CAS 104305-93-3)
- 2-Chloro-6-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyridine (CAS 1934633-19-8)
- N-(Cyclopropylmethyl)-N-methylamine Hydrochloride (CAS 77335-18-3)
- 5-Methoxypyrimidine-2,4-diamine (CAS 18588-48-2)
- 3-Bromo-5-methylthiophene-2-sulfonyl chloride (CAS 319002-81-8)
- 3-Bromo-3H-pyrazolo[3,4-d]pyrimidin-4-amine (CAS 570409-86-8)
- Tau Peptide (307-321) trifluoroacetate salt (CAS 330456-50-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com