5-Methoxypyrimidine-2,4-diamine CAS 18588-48-2
| CAS No. | 18588-48-2 |
| Molecular Formula | C5H8N4O |
| Molecular Weight | 140.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
5-Methoxypyrimidine-2,4-diamine (CAS 18588-48-2), molecular formula C5H8N4O and molecular weight 140.14 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-Methoxypyrimidine-2,4-diamine (C5H8N4O) is characterized by an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H8N4O |
| Molecular Weight | 140.14 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1962 |
| Nitrogen Atoms | 4 |
Related Methoxypyrimidine Standards
- 2-Methoxypyrimidine-4,6-diamine (CAS 856595-47-6)
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- 4-Methoxypyrimidine-2-methanamine (CAS 909563-18-4)
- 2-methoxypyrimidine-5-carbonitrile (CAS 38373-47-6)
- 4-methoxypyrimidine-2-carbonitrile (CAS 94789-37-4)
- 5-methoxypyrimidine-2-carbonitrile (CAS 87362-32-1)
- 5-Ethyl-2-methoxypyrimidine (CAS 156419-94-2)
- 5-Ethyl-4-methoxypyrimidine (CAS 53967-69-4)
Recommended Standards
- 3-Amino-1-methyl-1H-pyrrole-2-carboxylic acid (CAS 1823890-54-5)
- (1S,5R,6S)-2-Oxobicyclo[3.1.0]hexane-6-carboxylic acid (CAS 186541-47-9)
- 5-Amino-1-methylpyrazole-4-carboxamide (CAS 18213-75-7)
- 2-Cyclopenten-1-one, 3-(acetyloxy)- (CAS 18766-96-6)
- 1120258-93-6 Methyl (4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepin-3-yl)acetate MFCD13817366 (CAS 1120258-93-6)
- (2R,3R)-rel-3-(2,2,2-Trifluoroacetoxy)pyrrolidine-2-carboxylic acid (CAS 1788054-78-3)
- 3-(Trifluoromethyl)-2-(3,3,3-trifluoropropoxy)pyridine 1774897-87-8 (CAS 1774897-87-8)
- TERT-BUTYL 2-(6-CHLORO-5-FLUOROPYRIDIN-3-YL)ACETATE (CAS 1243246-09-4)
- N-tert-Butyloxycarbonyl-D-erythro-sphingosine-2,3-N,O-acetonide-1-phosphate Bis[1-(2-nitrophenyl)ethyl]ester (CAS 207516-26-5)
- 5-Bromoisoquinoline-4-carboxylic acid (CAS 1384251-84-6)
- N-(2,4-Dimethylphenyl)-3-(3-methoxyphenyl)-2-(2H-1,2,3,4-tetrazol-5-yl)propanamide (CAS 483993-30-2)
- 1-((tert-Butoxycarbonyl)-L-alanyl)piperidine-4-carboxylic acid (CAS 957023-71-1)
- 2,6-Dichlorotoluene-3,4,5-d3 (CAS 358731-95-0)
- Semaglutide impurity 77 (CAS CATO-C4X-222677)
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