Temozolomide Impurity 14 CAS 100-34-5
| CAS No. | 100-34-5 |
| Molecular Formula | C6H5N2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Temozolomide Impurity 14.
As a process- or degradation-related impurity, Temozolomide Impurity 14 (CAS 100-34-5, C6H5N2Cl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C6H5N2Cl, Temozolomide Impurity 14 contains a nitrile group, chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 140.57 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Temozolomide Impurity 14 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H5N2 Cl |
| Molecular Weight | 140.57 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Temozolomide Standards
- Temozolomide Impurity 13 (CAS 100191-43-3)
- Temozolomide Impurity 15 (CAS 100607-08-7)
- Temozolomide Impurity 22 (CAS 1114912-01-4)
- Temozolomide EP Impurity B (CAS 113942-30-6)
- Temozolomide EP Impurity C (CAS 114601-31-9)
- Temozolomide Metabolite-MTIC-d3 (CAS 1185242-69-6)
- Temozolomide Metabolite-MTIC (CAS 1232679-46-7)
- Temozolomide Impurity 26 (CAS 13114-72-2)
Recommended Standards
- Nemonoxacin Impurity 36 (CAS CATO-C4X-312836)
- Epalrestat Impurity 52 (CAS CATO-C4X-223652)
- Pyronaridine Impurity 20 (CAS CATO-C4X-297820)
- 898793-65-2 2-[3-(2,4-Dimethylphenyl)propanoyl]benzonitrile DTXSID50644670 (CAS 898793-65-2)
- ethyl 2-(chlorosulfonyl)-5-fluorobenzoate (CAS 1461706-64-8)
- 4-(2-methoxyphenyl)-2-(pyrrolidin-2-yl)-1H-imidazole dihydrochloride (CAS 1354951-81-7)
- 1-Octylnonyl 8-[(2-hydroxyethyl)[8-[(1-methylnonyl)oxy]-8-oxooctyl]amino]octanoate (CAS 2089251-73-8)
- 4-Phenylcyclohexanecarboxylic Acid (CAS 7494-76-0)
- Methyl 5-(aminomethyl)-2-nitrobenzoate (CAS 741228-89-7)
- Insulin Degludec Impurity 13 (CAS CATO-C4X-215713)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com