1,1,3,3,5,5,7,7-Octamethyltetrasiloxane CAS 1000-05-1

Purity 97%+In StockPharmaceutical Standards
CAS No.1000-05-1
Molecular FormulaC8H24O3Si4
Molecular Weight280.62 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1,1,3,3,5,5,7,7-Octamethyltetrasiloxane CAS 1000-05-1 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

1,1,3,3,5,5,7,7-Octamethyltetrasiloxane (CAS 1000-05-1), molecular formula C8H24O3Si4 and molecular weight 280.62 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 1,1,3,3,5,5,7,7-Octamethyltetrasiloxane (C8H24O3Si4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development.

As a certified reference material (CRM), 1,1,3,3,5,5,7,7-Octamethyltetrasiloxane meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC8H24O3Si4
Molecular Weight280.62 g/mol
Purity97%+
StorageStore in a cool place (≤25°C), keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityHygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)-3.0
CAS Registry Year (est.)1957

Related Octamethyltetrasiloxane Standards

Recommended Standards

Why CATO?