4-(2,4-Bis(trifluoromethyl)phenyl)-N-hydroxypicolinimidamide CAS 1219454-30-4
| CAS No. | 1219454-30-4 |
| Molecular Formula | C14H9F6N3O |
| Molecular Weight | 349.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 4-(2,4-Bis(trifluoromethyl)phenyl)-N-hydroxypicolinimidamide (CAS 1219454-30-4), a certified reference material (molecular formula C14H9F6N3O, MW 349.23 g/mol) for analytical method development and quality control.
4-(2,4-Bis(trifluoromethyl)phenyl)-N-hydroxypicolinimidamide (C14H9F6N3O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-(2,4-Bis(trifluoromethyl)phenyl)-N-hydroxypicolinimidamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H9F6N3O |
| Molecular Weight | 349.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Bis Standards
- 2-[[2,5-Bis(Trifluoromethyl)Phenyl]Amino]Benzoic Acid (CAS 102583-96-0)
- 4-(2,5-Bis(trifluoromethyl)phenyl)-N-hydroxypicolinimidamide (CAS 1219454-63-3)
- 5-(Trifluoromethyl)-3-{[5-(trifluoromethyl)pyridin-2-yl]sulfanyl}pyridine-2-carbonitrile (CAS 338396-86-4)
- 5-(Trifluoromethyl)-2-(3-(trifluoromethyl)-4,5,6,7-tetrahydro-1h-indazol-1-yl)aniline (CAS 937596-38-8)
- 2,4-bis(trifluoromethyl)imidazo[1,2-a][1,8] naphthyridine-8-carboxylic acid (CAS 439094-96-9)
- 4-(4-(3-(Trifluoromethyl)phenyl)thiazol-2-yl)benzoic acid (CAS 321430-15-3)
- 1-Methyl-4-{3-[5-(trifluoromethyl)pyridin-2-yl]benzoyl}piperazine (CAS 1092345-93-1)
- 1-Benzyl-4-[6-(trifluoromethyl)pyridine-3-carbonyl]piperazine (CAS 1092346-34-3)
Recommended Standards
- 2-Benzyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)isoindolin-1-one (CAS 1205683-45-9)
- tert-Butyl (5-methoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)carbamate (CAS 1186637-33-1)
- 4-Chloro-2-((4-chlorophenyl)thio)-1-phenyl-1h-imidazole-5-carbaldehyde (CAS 1235440-06-8)
- N-(pyridin-3-ylmethyl)-4,6-bis(trifluoromethyl)picolinamide (CAS 1092345-12-4)
- 4-Chloro-3-[(4-fluorophenyl)(prop-2-en-1-yl)sulfamoyl]benzoic acid (CAS 565192-80-5)
- 3-(6-Chloro-5-methylpyridin-3-yl)propan-1-amine (CAS 1393572-98-9)
- 4-(2-Methoxyethoxy)-1,2-benzisoxazol-3-amine (CAS 927802-21-9)
- (S)-2-amino-2-(1-(tert-butoxycarbonyl)azetidin-3-yl)acetic acid (CAS 1932383-98-6)
- tert-Butyl (S)-1-benzyl-5-oxopyrrolidine-2-carboxylate (CAS 90741-27-8)
- 4-(Methoxycarbonyl)-3-(trifluoromethyl)phenylboronic Acid Pinacol Ester (CAS 1045795-70-7)
- n-(3-Ethoxypropyl)-4-methylcyclohexan-1-amine (CAS 416868-93-4)
- (2-Bromo-6-(thiazol-4-yl)pyridin-4-yl)boronic acid (CAS 2225174-71-8)
- 2-(2,3-Dihydrobenzo[b][1,4]dioxine-6-carboxamido)butanoic acid (CAS 436855-75-3)
- Liraglutide Impurity 20 TFA Salt (CAS CATO-C4X-199220)
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