2-Chloro-1-(methylsulfonyl)-4-(trifluoromethyl)benzene CAS 1000339-68-3
| CAS No. | 1000339-68-3 |
| Molecular Formula | C8H6ClF3O2S |
| Molecular Weight | 258.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Chloro-1-(methylsulfonyl)-4-(trifluoromethyl)benzene (C8H6ClF3O2S) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
2-Chloro-1-(methylsulfonyl)-4-(trifluoromethyl)benzene (CAS 1000339-68-3), molecular formula C8H6ClF3O2S and molecular weight 258.65 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-Chloro-1-(methylsulfonyl)-4-(trifluoromethyl)benzene under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H6ClF3O2S |
| Molecular Weight | 258.65 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Cl-containing |
| Sulfur Atoms | 1 |
Related Chloro Standards
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Recommended Standards
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- Lamotrigine EP Impurity F (CAS 252186-79-1)
- Cis-benzyl 5-(hydroxymethyl)-2-(trifluoromethyl)piperidine-1-carboxylate (CAS 1951439-32-9)
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- Ethyl 4-cyano-3-hydroxy-5-methylsulfanylthiophene-2-carboxylate (CAS 203189-41-7)
- 1-(sec-Butyl)piperidin-4-ol (CAS 606489-66-1)
- endo-Gly31-Semaglutide (CAS CATO-C4X-2226282)
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