Lamotrigine EP Impurity F CAS 252186-79-1
| CAS No. | 252186-79-1 |
| Molecular Formula | C16H9Cl4N5O |
| Molecular Weight | 429.09 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Lamotrigine EP Impurity F (C16H9Cl4N5O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a process- or degradation-related impurity, Lamotrigine EP Impurity F (CAS 252186-79-1, C16H9Cl4N5O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Lamotrigine EP Impurity F under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H9Cl4N5O |
| Molecular Weight | 429.09 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >90% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related Lamotrigine Standards
- Lamotrigine-2N-glucuronide (CAS 135288-68-5)
- Lamotrigine 5 N Glucuronide (CAS 136565-77-0)
- Lamotrigine N2-Glucuronide (CAS 133310-19-7)
- Lamotrigine Impurity 22 (CAS CATO-C4X-167222)
- Lamotrigine impurity 19 (CAS CATO-C4X-167219)
- Lamotrigine Dimer Impurity 8 (CAS CATO-C4X-16728)
- Lamotrigine Dimer Impurity 9 (CAS 1797983-48-2)
- Lamotrigine N-Acetate (CAS 77668-57-6)
Recommended Standards
- Orbifloxacin impurity 14 (CAS CATO-C4X-256714)
- 5,6-Dibromo-2-(4-hydroxy-2-methylphenyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione (CAS 1217674-07-1)
- Pentafluorophenyl 4-amino-3-iodobenzoate (CAS 1086375-59-8)
- 9-Benzoyl-3,6-dibromo-9H-carbazole (CAS 912850-81-8)
- Vinpocetine Impurity 22 (CAS CATO-C4X-184322)
- Ipragliflozin Impurity 17 (CAS CATO-C4X-188517)
- Roxatidine impurity 72 (CAS CATO-C4X-121372)
- 5-Nitrothiophene-3-carboxylic Acid (CAS 40357-96-8)
- 3-Nitro-4-(phenylamino)benzonitrile (CAS 16588-23-1)
- (S)-Danicamtiv (CAS 1970972-75-8)
- 7-Iodo-5-nitrobenzofuran (CAS 478617-58-2)
- Ala-Ala-Phe p-nitroanilide (CAS 61043-41-2)
- 4-Ethyl-5-(4,5,6,7-tetrahydrobenzo[b]thiophen-3-yl)-4H-1,2,4-triazole-3-thiol (CAS 438230-58-1)
- Semaglutide Impurity 146 (CAS 2645421-68-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com