1-Bromo-2-fluoro-4-iodo-3-methylbenzene CAS 1000576-29-3
| CAS No. | 1000576-29-3 |
| Molecular Formula | C7H5BrFI |
| Molecular Weight | 314.92 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-Bromo-2-fluoro-4-iodo-3-methylbenzene is closely related to fluorine/bromine/iodine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 1-Bromo-2-fluoro-4-iodo-3-methylbenzene (CAS 1000576-29-3), a certified reference material (molecular formula C7H5BrFI, MW 314.92 g/mol) for analytical method development and quality control.
The molecular framework of 1-Bromo-2-fluoro-4-iodo-3-methylbenzene (C7H5BrFI) is characterized by fluorine/bromine/iodine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-Bromo-2-fluoro-4-iodo-3-methylbenzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H5BrFI |
| Molecular Weight | 314.92 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Br/I-containing |
Related Bromo Standards
- 3-Bromo-5-fluoro-4-iodotoluene (CAS 1000576-09-9)
- 6-Bromo-3-iodo-2-fluorotoluene (CAS 1114546-29-0)
- 2-Bromo-1-fluoro-5-iodo-3-methylbenzene (CAS 1356114-63-0)
- 5-Bromo-2-fluoro-1-iodo-3-methylbenzene (CAS 1627894-17-0)
- 2-Bromo-3-fluoro-4-iodo-1-methylbenzene (CAS 1804910-93-7)
- 1-Bromo-2-fluoro-3-iodo-5-methylbenzene (CAS 1805192-08-8)
- 1-Bromo-3-fluoro-5-iodo-2-methylbenzene (CAS 1805420-51-2)
- 1-Bromo-5-fluoro-3-iodo-2-methylbenzene (CAS 1805552-81-1)
Recommended Standards
- 5-Bromo-2-iodo-3-methoxypyrazine (CAS 476622-89-6)
- 1-(Bromomethyl)-3-fluoro-2-iodobenzene (CAS 1261675-04-0)
- 2-Bromo-5-iodo-3-methoxypyrazine (CAS 1935309-42-4)
- 1-(Bromomethyl)-3-fluoro-5-iodobenzene (CAS 1261759-75-4)
- 2',5'-Dichlorobiphenyl-3-carboxylic acid (CAS 1049036-18-1)
- O-Dimethylaminocarbonyl-4-(6-dimethylamino-4-trifluoromethylpyridin-2-yl)benzaldehyde oxime (CAS 1311283-83-6)
- 5-Fluoro-6-methyl-2-(trifluoromethyl)quinoline (CAS 537033-74-2)
- 1-(4-Fluorophenyl)pentan-1-amine (CAS 3823-26-5)
- 2-Iodo-9h-fluoren-9-one (CAS 3096-46-6)
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