Celecoxib Impurity 18 CAS 2247197-67-5
| CAS No. | 2247197-67-5 |
| Molecular Formula | C19H17F3N2O3S |
| Molecular Weight | 410.41 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Celecoxib Impurity 18 (CAS 2247197-67-5), a pharmacopoeial impurity reference standard (molecular formula C19H17F3N2O3S, MW 410.41 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C19H17F3N2O3S, Celecoxib Impurity 18 contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 410.41 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Celecoxib Impurity 18 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H17F3N2O3S |
| Molecular Weight | 410.41 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Celecoxib Standards
- Celecoxib Impurity 3(Celecoxib Carboxylic Acid) (CAS 170571-01-4)
- Celecoxib Impurity 51 (CAS CATO-C4X-104351)
- Celecoxib Impurity 65 (CAS CATO-C4X-104365)
- Celecoxib Impurity 23 (CAS 2247197-65-3)
- Celecoxib Impurity 73 (CAS CATO-C4X-104373)
- Celecoxib Impurity 41 (CAS 1803258-57-2)
- Celecoxib Impurity 46 (CAS CATO-C4X-104346)
- Celecoxib Impurity 76 (CAS CATO-C4X-104376)
Recommended Standards
- N-allyl-2-(6-oxo-1-(3-(trifluoromethyl)benzyl)-1,6-dihydropyridine-3-carbonyl)hydrazine-1-carbothioamide (CAS 477852-93-0)
- Flurbiprofen Impurity 69 (CAS CATO-C4X-144469)
- N-(2,4-Difluorophenyl)-4-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]benzamide (CAS 321430-17-5)
- Ethametsulfuron-Methyl (CAS 97780-06-8)
- Sunitinib Impurity 60 (CAS CATO-C4X-133360)
- Quetiapine EP Impurity V DiHCl (CAS 2204369-14-0 (free base))
- Arbidol Impurity 38 (CAS CATO-C4X-112938)
- 1,2,3,4,5,6-Hexahydrobenzo[b][1,5]diazocine (CAS 13481-83-9)
- DL-4-Hydroxyphenyllactic Acid (CAS 306-23-0)
- Methyl 2-(4-methyl-1,3-thiazol-2-yl)acetate (CAS 117840-81-0)
- 2-Amino-N-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-3-sulfonamide (CAS 1416337-96-6)
- Methyl 1-(difluoromethyl)-1H-pyrazole-3-carboxylate (CAS 1310351-03-1)
- 4-Cyclopropoxy-3-ethylbenzonitrile (CAS 1243482-68-9)
- Osteogenic Growth Peptide (10-14) (CAS 105250-85-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com