5-Bromo-3-chloro-2-fluorobenzonitrile CAS 1000577-76-3
| CAS No. | 1000577-76-3 |
| Molecular Formula | C7H2BrClFN |
| Molecular Weight | 234.45 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 5-Bromo-3-chloro-2-fluorobenzonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 5-Bromo-3-chloro-2-fluorobenzonitrile (CAS 1000577-76-3), a certified reference material (molecular formula C7H2BrClFN, MW 234.45 g/mol) for analytical method development and quality control.
5-Bromo-3-chloro-2-fluorobenzonitrile (C7H2BrClFN) contains a nitrile group, fluorine/chlorine/bromine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C7H2BrClFN |
| Molecular Weight | 234.45 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Cl/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 4-Bromo-2-chloro-5-fluorobenzonitrile (CAS 1126779-33-6)
- 3-Bromo-5-chloro-2-fluorobenzonitrile (CAS 1160574-15-1)
- 4-Bromo-3-chloro-2-fluorobenzonitrile (CAS 1160574-68-4)
- 4-Bromo-5-chloro-2-fluorobenzonitrile (CAS 1349716-15-9)
- 3-Bromo-4-chloro-5-fluorobenzonitrile (CAS 1357944-86-5)
- 3-Bromo-2-chloro-6-fluorobenzonitrile (CAS 1421620-33-8)
- 4-Bromo-2-chloro-3-fluorobenzonitrile (CAS 1427439-32-4)
- 4-Bromo-3-chloro-5-fluorobenzonitrile (CAS 1427439-38-0)
Recommended Standards
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- Triethylsilyl 2-methylprop-2-ene-1-sulfinate (CAS 850418-19-8)
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- 2-(Piperidin-4-yloxy)pyrimidine dihydrochloride (CAS 950649-19-1)
- 1-(5-Bromo-2-(2,2,2-trifluoroethoxy)phenyl)adamantane (CAS 929000-50-0)
- 1-Amino-2-(2-fluorophenyl)propan-2-ol (CAS 133562-29-5)
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- Empagliflozin Impurity 149 (CAS CATO-C4X-1065149)
- 6-(Trifluoromethoxy)quinolin-3-ol (CAS 1261868-42-1)
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