3-Bromo-4-chloro-5-fluorobenzonitrile CAS 1357944-86-5
| CAS No. | 1357944-86-5 |
| Molecular Formula | C7H2BrClFN |
| Molecular Weight | 234.45 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
3-Bromo-4-chloro-5-fluorobenzonitrile (CAS 1357944-86-5) is a high-purity analytical reference standard with the molecular formula C7H2BrClFN and a molecular weight of 234.45 g/mol.
3-Bromo-4-chloro-5-fluorobenzonitrile (C7H2BrClFN) contains a nitrile group, fluorine/chlorine/bromine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 3-Bromo-4-chloro-5-fluorobenzonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H2BrClFN |
| Molecular Weight | 234.45 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 5-Bromo-3-chloro-2-fluorobenzonitrile (CAS 1000577-76-3)
- 4-Bromo-2-chloro-5-fluorobenzonitrile (CAS 1126779-33-6)
- 3-Bromo-5-chloro-2-fluorobenzonitrile (CAS 1160574-15-1)
- 4-Bromo-3-chloro-2-fluorobenzonitrile (CAS 1160574-68-4)
- 4-Bromo-5-chloro-2-fluorobenzonitrile (CAS 1349716-15-9)
- 3-Bromo-2-chloro-6-fluorobenzonitrile (CAS 1421620-33-8)
- 4-Bromo-2-chloro-3-fluorobenzonitrile (CAS 1427439-32-4)
- 4-Bromo-3-chloro-5-fluorobenzonitrile (CAS 1427439-38-0)
Recommended Standards
- 2-Bromo-4-chloro-3-fluorobenzonitrile (CAS 1430115-47-1)
- 6-Bromo-3-chloro-2-fluorobenzonitrile (CAS 1779124-51-4)
- 1,1,3,3,5,5, Hexamethyl diethoxy trisiloxane (CAS 75144-60-4)
- 2-Bromo-3-chloro-6-fluorobenzonitrile (CAS 1823576-81-3)
- 2-[(2-hydroxyphenyl)sulfanyl]acetohydrazide (CAS 20277-06-9)
- Methylammonium Acetate (CAS 6998-30-7)
- 4-Amino-5-chlorobenzene-1,3-disulfonamide (CAS 1083-36-9)
- (5-(4-Fluorophenyl)-1H-1,2,4-triazol-3-yl)methanamine (CAS 944905-95-7)
- 2-(4,7-Dihydro-5H-thieno[2,3-c]pyran-7-yl)acetic acid (CAS 1258649-72-7)
- 1-Benzyl-3-chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trimethylsilyl)pyridin-2(1H)-one (CAS 1010101-15-1)
- 3-Fluoro-3-thiomorpholinomethyl benzophenone (CAS 898763-07-0)
- (R/S)-N-Deacetyl Colchicine (CAS 102491-73-6)
- N-Chloromorpholine (CAS 23328-69-0)
- D-Pro31-Tirzepatide (CAS CATO-CPTD788905)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com