Isopropyl 4-(2-chlorophenyl)-1-ethyl-2-methyl-5-oxo-1,4,5,7-tetrahydrofuro[3,4-b]pyridine-3-carboxylate CAS 100276-03-7
| CAS No. | 100276-03-7 |
| Molecular Formula | C20H22ClNO4 |
| Molecular Weight | 375.85 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Isopropyl 4-(2-chlorophenyl)-1-ethyl-2-methyl-5-oxo-1,4,5,7-tetrahydrofuro[3,4-b]pyridine-3-carboxylate (CAS 100276-03-7), molecular formula C20H22ClNO4 and molecular weight 375.85 g/mol, is a CATO reference standard with documented purity and traceability.
Isopropyl 4-(2-chlorophenyl)-1-ethyl-2-methyl-5-oxo-1,4,5,7-tetrahydrofuro[3,4-b]pyridine-3-carboxylate (C20H22ClNO4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H22ClNO4 |
| Molecular Weight | 375.85 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
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- Isopropyl 5-chloro-1-(2,4-dichlorobenzyl)-6-oxo-1,6-dihydropyridine-3-carboxylate (CAS 242471-96-1)
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Recommended Standards
- ethyl 3,4,5-tribromopyrrole-2-carboxylate (CAS 740813-36-9)
- 1-((5-Chlorothiophen-2-yl)sulfonyl)-N-(3-methylisoxazol-5-yl)pyrrolidine-2-carboxamide (CAS 1219438-34-2)
- (R)-L 888607 (CAS 2446042-90-4)
- 2-[1-(2-Chloro-acetyl)-piperidin-4-ylmethyl]-6-(4-methoxy-phenyl)-2H-pyridazin-3-one (CAS 1229626-96-3)
- 1-((2-Nitrophenyl)sulfonyl)piperidin-4-one (CAS 267666-09-1)
- Arjunolic acid (CAS 465-00-9)
- 2,3-Dichloro-6- Nitroquinoxaline (CAS 2379-60-4)
- 3-Phenylisoxazol-5-yl 3-(trifluoromethyl)benzoate (CAS 303987-02-2)
- N-Butyl-1-(p-tolyl)-1H-1,2,3-triazole-4-carboxamide (CAS 951611-26-0)
- Iodofenphos (CAS 18181-70-9)
- Ethyl 2-((4-fluorobenzyl)(4-(trifluoromethyl)phenyl)amino)thiazole-4-carboxylate (CAS 860783-96-6)
- N-Methyl-5,6,7,8-tetrahydroquinolin-8-amine (CAS 878025-42-4)
- Tedizolid Impurity 46 (CAS 171018-16-9)
- Tirzepatide Impurity 35 (CAS CATO-C4X-324035)
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