2-[1-(2-Chloro-acetyl)-piperidin-4-ylmethyl]-6-(4-methoxy-phenyl)-2H-pyridazin-3-one CAS 1229626-96-3
| CAS No. | 1229626-96-3 |
| Molecular Formula | C19H22ClN3O3 |
| Molecular Weight | 375.85 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-[1-(2-Chloro-acetyl)-piperidin-4-ylmethyl]-6-(4-methoxy-phenyl)-2H-pyridazin-3-one is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2-[1-(2-Chloro-acetyl)-piperidin-4-ylmethyl]-6-(4-methoxy-phenyl)-2H-pyridazin-3-one (CAS 1229626-96-3), a certified reference material (molecular formula C19H22ClN3O3, MW 375.85 g/mol) for analytical method development and quality control.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 2-[1-(2-Chloro-acetyl)-piperidin-4-ylmethyl]-6-(4-methoxy-phenyl)-2H-pyridazin-3-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 375.85 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-[1-(2-Chloro-acetyl)-piperidin-4-ylmethyl]-6-(4-methoxy-phenyl)-2H-pyridazin-3-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H22ClN3O3 |
| Molecular Weight | 375.85 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 7-Chloro-4-(3,4-diethoxybenzyl)-4,5-dihydrobenzo[f][1,4]oxazepin-3(2H)-one (CAS 1326937-73-8)
- 4-(2-Chloro-6-fluorophenyl)-6-methyl-N-phenyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide (CAS 183231-05-2)
- 2-(1-(3-Chloro-4-morpholinophenyl)-2,5-dimethyl-1H-pyrrol-3-yl)-N-methyl-2-oxoacetamide (CAS 860610-29-3)
- (E)-({6-chloro-2-phenylimidazo[1,2-a]pyridin-3-yl}methylidene)[(3-methylphenyl)methoxy]amine 478257-25-9 8P-664S (CAS 478257-25-9)
- 1-{[6-Chloro-2-(thiophen-2-yl)imidazo[1,2-a]pyridin-3-yl]methyl}piperidine-4-carboxylic acid (CAS 893612-77-6)
- 4-(3-chloro-4-methylphenyl)-5-[(4-ethoxyphenoxy)methyl]-4H-1,2,4-triazole-3-thiol (CAS 723332-61-4)
- 5-(4-Chloro-2-methylphenoxymethyl)-4-(4-ethoxyphenyl)-4H-1,2,4-triazole-3-thiol (CAS 748793-44-4)
- Methyl 3-({2-[(4-chloro-1-naphthyl)oxy]acetyl}amino)-2-thiophenecarboxylate (CAS 478033-17-9)
Recommended Standards
- 1-((5-Chlorothiophen-2-yl)sulfonyl)-N-(3-methylisoxazol-5-yl)pyrrolidine-2-carboxamide (CAS 1219438-34-2)
- (S)-2-((tert-butoxycarbonyl)amino)-3-(4'-chloro-[1,1'-biphenyl]-4-yl)propanoic acid (CAS 1282042-74-3)
- Isopropyl 4-(2-chlorophenyl)-1-ethyl-2-methyl-5-oxo-1,4,5,7-tetrahydrofuro[3,4-b]pyridine-3-carboxylate (CAS 100276-03-7)
- ethyl 3,4,5-tribromopyrrole-2-carboxylate (CAS 740813-36-9)
- 1-Isopropyl-1H-pyrazole-4-carbaldehyde (CAS 313735-67-0)
- racemic cis-6-Oxo-octahydro-pyrrolo[3,4-c]pyridine-2-carboxylic acid tert-butyl ester (CAS 1251004-07-5)
- 3-Ethoxy-5-iodo-4-propoxybenzoic acid (CAS 723245-46-3)
- Buspirone Impurity N1 (CAS 5662-95-3)
- 3-Methyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4(3H)-one (CAS 1510384-26-5)
- 5-Benzyl-7,7-difluoro-4,5,6,7-tetrahydroisoxazolo[4,5-c]pyridin-3-ol (CAS 1823265-27-5)
- 4-formyl-2-methoxyphenyl benZoate (CAS 790-16-9)
- 2-Methyl-5-phenylpyrimidin-4(1H)-one (CAS 343944-83-2)
- 2-(2,3-Dibromo-6-ethoxy-4-formylphenoxy)-N-(p-tolyl)acetamide (CAS 832673-73-1)
- Hepcidin/LEAP-1 (Human); Liver-Expressed Antimicrobial Peptide (CAS 342790-21-0)
Why CATO?
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