N-((2,5-Dichloro-4-((1,1,2,2-tetrafluoroethyl)thio)phenyl)carbamoyl)-2,6-difluorobenzamide CAS 100279-18-3
| CAS No. | 100279-18-3 |
| Molecular Formula | C16H8Cl2F6N2O2S |
| Molecular Weight | 477.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies N-((2,5-Dichloro-4-((1,1,2,2-tetrafluoroethyl)thio)phenyl)carbamoyl)-2,6-difluorobenzamide (CAS 100279-18-3), a certified reference material (molecular formula C16H8Cl2F6N2O2S, MW 477.21 g/mol) for analytical method development and quality control.
N-((2,5-Dichloro-4-((1,1,2,2-tetrafluoroethyl)thio)phenyl)carbamoyl)-2,6-difluorobenzamide (C16H8Cl2F6N2O2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), N-((2,5-Dichloro-4-((1,1,2,2-tetrafluoroethyl)thio)phenyl)carbamoyl)-2,6-difluorobenzamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H8Cl2F6N2O2S |
| Molecular Weight | 477.21 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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Recommended Standards
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- N-(3-chloro-4-methylphenyl)-2-((4,6-dimethylpyrimidin-2-yl)thio)acetamide (CAS 312266-80-1)
- Porphobilinogen (CAS 487-90-1)
- 5-Cyclopropoxy-2-isopropylnicotinonitrile (CAS 1243322-91-9)
- 2,4-Dichloro-5,6,7,8-tetrahydro-pyrido[3,2-d]pyrimidine (CAS 1260669-81-5)
- Liraglutide Impurity 14 TFA Salt (CAS CATO-C4X-199214)
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