(3-Chloro-5-fluoro-4-hydroxyphenyl)boronic acid CAS 1003298-72-3
| CAS No. | 1003298-72-3 |
| Molecular Formula | C6H5BClFO3 |
| Molecular Weight | 190.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(3-Chloro-5-fluoro-4-hydroxyphenyl)boronic acid (CAS 1003298-72-3) is a high-purity analytical reference standard with the molecular formula C6H5BClFO3 and a molecular weight of 190.36 g/mol.
(3-Chloro-5-fluoro-4-hydroxyphenyl)boronic acid (C6H5BClFO3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (3-Chloro-5-fluoro-4-hydroxyphenyl)boronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H5BClFO3 |
| Molecular Weight | 190.36 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 3-Chloro-4-fluoro-5-hydroxyphenylboronic acid (CAS 1379466-81-5)
- (4-Chloro-2-fluoro-3-hydroxyphenyl)boronic acid (CAS 1451393-13-7)
- (3-Chloro-2-fluoro-6-hydroxyphenyl)boronic acid (CAS 2573799-47-8)
- (3-Chloro-6-fluoro-2-hydroxyphenyl)boronic acid (CAS 2134622-97-0)
- 2-Chloro-6-fluoro-3-hydroxyphenylboronic Acid (CAS 957121-07-2)
- 2-Chloro-6-fluoro-5-hydroxyphenylboronic acid (CAS 958646-67-8)
- 3-Chloro-5-fluoro-2-hydroxyphenylboronic acid (CAS 2121515-30-6)
- 4-Chloro-3-fluoro-2-hydroxyphenylboronic acid (CAS 2445448-80-4)
Recommended Standards
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- 2-Morpholinoisonicotinicacidhydrochloride (CAS 848580-46-1)
- 3-Cyclopropoxy-2-fluoroisonicotinaldehyde (CAS 1243344-29-7)
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- (Z)-N-[(2,3-Dihydro-1H-indol-1-yl)(3-nitrophenyl)methylidene]hydroxylamine (CAS 692288-01-0)
- Acesulfame impurity 4 (CAS 459454-05-8)
- 2-(3,4-Dimethoxybenzoyl)-1H-indene-1,3(2H)-dione (CAS 374722-15-3)
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- Prolactin-Releasing Peptide (12-31), rat (CAS 222988-10-5)
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