4-Chloro-3-fluoro-2-hydroxyphenylboronic acid CAS 2445448-80-4
| CAS No. | 2445448-80-4 |
| Molecular Formula | C6H5BClFO3 |
| Molecular Weight | 190.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Chloro-3-fluoro-2-hydroxyphenylboronic acid (CAS 2445448-80-4) is a high-purity analytical reference standard with the molecular formula C6H5BClFO3 and a molecular weight of 190.36 g/mol.
Based on its molecular formula C6H5BClFO3, 4-Chloro-3-fluoro-2-hydroxyphenylboronic acid contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 190.36 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-Chloro-3-fluoro-2-hydroxyphenylboronic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H5BClFO3 |
| Molecular Weight | 190.36 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- (3-Chloro-5-fluoro-4-hydroxyphenyl)boronic acid (CAS 1003298-72-3)
- 3-Chloro-4-fluoro-5-hydroxyphenylboronic acid (CAS 1379466-81-5)
- (4-Chloro-2-fluoro-3-hydroxyphenyl)boronic acid (CAS 1451393-13-7)
- (3-Chloro-2-fluoro-6-hydroxyphenyl)boronic acid (CAS 2573799-47-8)
- (3-Chloro-6-fluoro-2-hydroxyphenyl)boronic acid (CAS 2134622-97-0)
- 2-Chloro-6-fluoro-3-hydroxyphenylboronic Acid (CAS 957121-07-2)
- 2-Chloro-6-fluoro-5-hydroxyphenylboronic acid (CAS 958646-67-8)
- 3-Chloro-5-fluoro-2-hydroxyphenylboronic acid (CAS 2121515-30-6)
Recommended Standards
- 5-Chloro-2-fluoro-4-hydroxyphenylboronic acid (CAS 2121512-43-2)
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- B-(4-Chloro-2-fluoro-6-hydroxyphenyl)boronic acid (CAS 2470930-46-0)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com