Paroxetine Impurity 43 CAS 100332-20-5
| CAS No. | 100332-20-5 |
| Molecular Formula | C13H18FNO |
| Molecular Weight | 223.29 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Paroxetine Impurity 43.
CATO supplies Paroxetine Impurity 43 (CAS 100332-20-5), a pharmacopoeial impurity reference standard (molecular formula C13H18FNO, MW 223.29 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Paroxetine Impurity 43 (C13H18FNO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 223.29 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H18FNO |
| Molecular Weight | 223.29 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Paroxetine Standards
- Paroxetine Impurity 19 (CAS 318279-38-8)
- Paroxetine impurity 20 (CAS 389573-45-9)
- Paroxetine Impurity 24 (CAS 105812-81-5)
- Paroxetine Impurity 53 (CAS 109887-53-8)
- Paroxetine Impurity 62 (CAS 100332-12-5)
- Paroxetine Impurity 7 (CAS CATO-C4X-10357)
- Paroxetine Impurity 22 (CAS 127017-78-1)
- Paroxetine Impurity N1 (Mixture of Diastereomers) (CAS 216690-19-6)
Recommended Standards
- 946725-20-8 4-{[(3-Fluorophenyl)methoxy]methyl}piperidine DTXSID80649875 (CAS 946725-20-8)
- Pramipexole Impurity 54 (CAS CATO-C4X-110754)
- N-methyl-2-(2-phenylacetyl)hydrazine-1-carbothioamide (CAS 51291-26-0)
- Faropenem Impurity 22 (CAS CATO-C4X-128922)
- Relugolix Impurity 90 (CAS CATO-C4X-242990)
- Mesalazine EP Impurity P (CAS 887256-40-8)
- Oseltamivir impurity 232 (CAS CATO-C4X-1720232)
- 5-(Pyrimidin-2-ylthio)furan-2-carbaldehyde (CAS 57603-82-4)
- 23-Methyl-3,6,9,12,15-pentaoxatetracosan-1-ol (CAS 66172-86-9)
- (E)-N-(3-chloro-2,4-difluorophenyl)-3-(furan-2-yl)acrylamide (CAS 400078-31-1)
- 1-(1-phenyl-1,3,4,9-tetrahydro-2H-pyrido[3,4-b]indol-2-yl)pentan-1-one (CAS 334939-35-4)
- 2-{[5-chloro-1-(4-methoxyphenyl)-6-oxo-1,6-dihydropyridazin-4-yl](methyl)amino}ethyl cyclopropanecarboxylate (CAS 477867-34-8)
- Erythromycin Impurity 49 (CAS 229318-98-3)
- Tirzepatide Impurity 37 (CAS CATO-C4X-324037)
Why CATO?
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